Product Information
SPIRONOLACTONE 25 MG TABLET is a generic product labeled by McKesson, priced at $0.0458 per EA under NDC 63739054410. Its NADAC has been published 640 times since Nov 28, 2013.
FDA first approved this application on Jul 2, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The Low Outlier badge above means this manufacturer's average price in the Spironolactone market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
25 mg/1
Manufacturer
McKessonNDC
63739054410
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
2/18/2026
Active Ingredients
SPIRONOLACTONEApproval Type
Generic (ANDA)
FDA Application
ANDA091426FDA Approved
7/2/2010
TE Code
AB
On Market Since
8/2/2010
Pharmacological Classes
Price Statistics
The NADAC for SPIRONOLACTONE 25 MG TABLET has been published 640 times since Nov 28, 2013, and over the history we have for it it has declined 41.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0458 per EA |
|---|---|
| All-time high | $0.0866 (Feb 12, 2014) |
| All-time low | $0.0410 (Nov 20, 2024) |
| 52-week high | $0.0505 |
| 52-week low | $0.0458 |
| Median price | $0.0592 |
| Average price | $0.0599 |
| Largest weekly change | -20.9% (Nov 20, 2024) |
| Weeks tracked | 640 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
0.0%
1Y
-9.3%
3Y
-12.5%
5Y
-22.1%
All
-41.3%
Last surveyed Feb 25, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 6% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SPIRONOLACTONE 25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SPIRONOLACTONE 25 MG TABLET, manufactured by McKesson, is $0.0458 per EA (NDC 63739054410), effective Feb 25, 2026.
How has the price of SPIRONOLACTONE 25 MG TABLET changed over time?
Over the history we have for it, the NADAC for SPIRONOLACTONE 25 MG TABLET has declined 41.3%. It has been tracked across 640 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SPIRONOLACTONE 25 MG TABLET?
Since Nov 28, 2013, the NADAC for SPIRONOLACTONE 25 MG TABLET has ranged from a low of $0.0410 (Nov 20, 2024) to a high of $0.0866 (Feb 12, 2014), with a median of $0.0592 per EA.
Are there cheaper alternatives to SPIRONOLACTONE 25 MG TABLET?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SPIRONOLACTONE 25 MG TABLET, is $0.0430 per EA — about 6% below SPIRONOLACTONE 25 MG TABLET.
Who manufactures SPIRONOLACTONE 25 MG TABLET?
SPIRONOLACTONE 25 MG TABLET (NDC 63739054410) is labeled by McKesson, and CMS classifies it as a generic product.