Product Information

TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $0.1054 per EA under NDC 53746061705. Its NADAC has been published 642 times since Mar 12, 2014.

TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB

Tramadol Hydrochloride and Acetaminophen
$0.1054per EA
DEA Schedule CIV

Strength

325; 37.5 mg/1; mg/1

NDC

53746061705

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA090485

On Market Since

12/17/2009

Pharmacological Classes

Full Opioid Agonists
Opioid Agonist

Price Statistics

The NADAC for TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB has been published 642 times since Mar 12, 2014, and over the history we have for it it has declined 52.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1054 per EA
All-time high$0.2270 (May 13, 2015)
All-time low$0.0806 (Nov 20, 2024)
52-week high$0.1145
52-week low$0.1014
Median price$0.1291
Average price$0.1454
Largest weekly change-29.5% (Jan 18, 2017)
Weeks tracked642
Tracking sinceMar 12, 2014

Price History

1W

0.0%

1M

-0.1%

3M

+3.9%

6M

-6.3%

1Y

-4.0%

3Y

+0.3%

5Y

-6.7%

All

-52.1%

Generic Alternatives

The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB, manufactured by Amneal Pharmaceuticals of New York LLC, is $0.1054 per EA (NDC 53746061705), effective Jun 24, 2026.

How has the price of TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB changed over time?

Over the history we have for it, the NADAC for TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB has declined 52.1%. It has been tracked across 642 weekly CMS publications since Mar 12, 2014.

What are the highest and lowest recorded NADAC prices for TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB?

Since Mar 12, 2014, the NADAC for TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB has ranged from a low of $0.0806 (Nov 20, 2024) to a high of $0.2270 (May 13, 2015), with a median of $0.1291 per EA.

Are there cheaper alternatives to TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB?

3 NADAC-published products share the same active ingredient, strength, and dosage form as TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB, but none are currently priced below it.

Who manufactures TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB?

TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB (NDC 53746061705) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.