This NDC is on FDA's drug shortage list (posted Dec 15, 2021)

Reported reason: Demand increase for the drug

Product Information

METHYLPREDNISOLONE 400 MG/5 ML is a generic product labeled by Eugia US LLC, priced at $13.4236 per ML under NDC 55150031401. Its NADAC has been published 29 times since Sep 18, 2024.

FDA first approved this application on Apr 13, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METHYLPREDNISOLONE 400 MG/5 ML

Methylprednisolone Acetate
$13.4236per ML

Strength

80 mg/mL

Manufacturer

Eugia US LLC

NDC

55150031401

Classification

Generic

Dosage Form

INJECTION, SUSPENSION

Route

INTRA-ARTICULAR; INTRALESIONAL; INTRAMUSCULAR; SOFT TISSUE

Effective Date

3/19/2025

Active Ingredients

METHYLPREDNISOLONE ACETATE

Approval Type

Generic (ANDA)

FDA Application

ANDA211930

FDA Approved

4/13/2023

TE Code

AB

On Market Since

4/13/2023

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for METHYLPREDNISOLONE 400 MG/5 ML has been published 29 times since Sep 18, 2024, and over the history we have for it it has declined 10.3%. The table below summarizes its recorded NADAC range and movement.

Current price$13.4236 per ML
All-time high$14.9732 (Oct 16, 2024)
All-time low$13.4236 (Mar 19, 2025)
Median price$14.0949
Average price$14.1173
Largest weekly change-5.1% (Oct 23, 2024)
Weeks tracked29
Tracking sinceSep 18, 2024

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

N/A

5Y

N/A

All

-10.3%

Last surveyed Apr 2, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 3%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of METHYLPREDNISOLONE 400 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for METHYLPREDNISOLONE 400 MG/5 ML, manufactured by Eugia US LLC, is $13.4236 per ML (NDC 55150031401), effective Apr 2, 2025.

How has the price of METHYLPREDNISOLONE 400 MG/5 ML changed over time?

Over the history we have for it, the NADAC for METHYLPREDNISOLONE 400 MG/5 ML has declined 10.3%. It has been tracked across 29 weekly CMS publications since Sep 18, 2024.

What are the highest and lowest recorded NADAC prices for METHYLPREDNISOLONE 400 MG/5 ML?

Since Sep 18, 2024, the NADAC for METHYLPREDNISOLONE 400 MG/5 ML has ranged from a low of $13.4236 (Mar 19, 2025) to a high of $14.9732 (Oct 16, 2024), with a median of $14.0949 per ML.

Are there cheaper alternatives to METHYLPREDNISOLONE 400 MG/5 ML?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METHYLPREDNISOLONE 400 MG/5 ML, is $13.0533 per ML — about 3% below METHYLPREDNISOLONE 400 MG/5 ML.

Who manufactures METHYLPREDNISOLONE 400 MG/5 ML?

METHYLPREDNISOLONE 400 MG/5 ML (NDC 55150031401) is labeled by Eugia US LLC, and CMS classifies it as a generic product.

Is METHYLPREDNISOLONE 400 MG/5 ML in shortage?

Yes — NDC 55150031401 is currently listed in FDA's drug shortage database (posted Dec 15, 2021). Reported reason: Demand increase for the drug.