Product Information

PIOGLITAZONE-METFORMIN 15-500 is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.3220 per EA under NDC 57237021760. Its NADAC has been published 514 times since Oct 19, 2016.

FDA first approved this application on Feb 13, 2013. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PIOGLITAZONE-METFORMIN 15-500

Pioglitazone Hydrochloride and Metformin Hydrochloride
$0.3220per EA

Strength

500; 15 mg/1; mg/1

NDC

57237021760

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA200823

FDA Approved

2/13/2013

TE Code

AB

On Market Since

2/13/2013

Pharmacological Classes

Biguanide
Biguanides
Peroxisome Proliferator Receptor alpha Agonist
Peroxisome Proliferator Receptor gamma Agonist
Peroxisome Proliferator-activated Receptor alpha Agonists
Peroxisome Proliferator-activated Receptor gamma Agonists
Thiazolidinedione
Thiazolidinediones

Price Statistics

The NADAC for PIOGLITAZONE-METFORMIN 15-500 has been published 514 times since Oct 19, 2016, and over the history we have for it it has declined 78.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3220 per EA
All-time high$1.6818 (Mar 15, 2017)
All-time low$0.1994 (Apr 19, 2023)
52-week high$0.5670
52-week low$0.3220
Median price$0.6575
Average price$0.6968
Largest weekly change+79.1% (Apr 17, 2024)
Weeks tracked514
Tracking sinceOct 19, 2016

Price History

1W

-14.5%

1M

-14.5%

3M

-21.5%

6M

-14.5%

1Y

-43.2%

3Y

-17.9%

5Y

-49.1%

All

-78.6%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PIOGLITAZONE-METFORMIN 15-500?

The current National Average Drug Acquisition Cost (NADAC) for PIOGLITAZONE-METFORMIN 15-500, manufactured by Rising Pharma Holdings Inc., is $0.3220 per EA (NDC 57237021760), effective Aug 19, 2026.

How has the price of PIOGLITAZONE-METFORMIN 15-500 changed over time?

Over the history we have for it, the NADAC for PIOGLITAZONE-METFORMIN 15-500 has declined 78.6%. It has been tracked across 514 weekly CMS publications since Oct 19, 2016.

What are the highest and lowest recorded NADAC prices for PIOGLITAZONE-METFORMIN 15-500?

Since Oct 19, 2016, the NADAC for PIOGLITAZONE-METFORMIN 15-500 has ranged from a low of $0.1994 (Apr 19, 2023) to a high of $1.6818 (Mar 15, 2017), with a median of $0.6575 per EA.

Are there cheaper alternatives to PIOGLITAZONE-METFORMIN 15-500?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PIOGLITAZONE-METFORMIN 15-500 in a comparable dosage form, but none are currently priced below it.

Who manufactures PIOGLITAZONE-METFORMIN 15-500?

PIOGLITAZONE-METFORMIN 15-500 (NDC 57237021760) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.