Back to Market Feed

Product Information

M-DRYL 12.5 MG/5 ML SOLUTION is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.0196 per ML under NDC 58657052804. Its NADAC has been published 123 times since Apr 17, 2024.

M-DRYL 12.5 MG/5 ML SOLUTION

DIPHENHYDRAMINE HYDROCHLORIDE
$0.0196per ML
OTC

Strength

12.5 mg/5mL

NDC

58657052804

Classification

Generic

Dosage Form

LIQUID

Route

ORAL

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

8/1/2019

Pharmacological Classes

Histamine H1 Receptor Antagonists
Histamine-1 Receptor Antagonist

Price Statistics

The NADAC for M-DRYL 12.5 MG/5 ML SOLUTION has been published 123 times since Apr 17, 2024, and over the history we have for it it has declined 30.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0196 per ML
All-time high$0.0282 (Jul 10, 2024)
All-time low$0.0164 (Feb 12, 2025)
52-week high$0.0199
52-week low$0.0173
Median price$0.0192
Average price$0.0215
Largest weekly change-40.1% (Feb 12, 2025)
Weeks tracked123
Tracking sinceApr 17, 2024

Price History

1W

-1.1%

1M

-1.1%

3M

-1.3%

6M

+5.0%

1Y

+8.3%

3Y

N/A

5Y

N/A

All

-30.3%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 11% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 11%

1 alternative • Same active ingredient

M-DRYL 12.5 MG/5 ML SOLUTION
Generic
58657052816•Method Pharmaceuticals LLC
$0.0175
Save 11%

Related Drugs

Same classification

GS SLEEP TIME 50 MG/30 ML LIQ
Generic
00113018640•L. Perrigo Company
$0.0085
per ML
GNP SLEEP AID 50 MG/30 ML LIQ
Generic
46122075429•AmerisourceBergen
$0.0085
per ML
PV FLU RELIEF THERAPY LIQUID
Generic
68016015408•Chain Drug Marketing Association
$0.0121
per ML
QC EZZ NITE SLEEP 50 MG/30 ML
Generic
83324001506•Chain Drug Marketing Association
$0.0136
per ML
CHILD'S ALLERGY 12.5 MG/5 ML
Generic
36800037934•Topco Associates LLC
$0.0143
per ML
CHILD'S ALLERGY 12.5 MG/5 ML
Generic
36800037926•Topco Associates LLC
$0.0145
per ML
QC CHILD ALLERGY 12.5 MG/5 ML
Generic
63868037004•Chain Drug Marketing Association
$0.0155
per ML
QC CHILD ALLERGY 12.5 MG/5 ML
Generic
63868082354•Chain Drug Marketing Association
$0.0155
per ML
CHILD ALLERGY RLF 12.5 MG/5 ML
Generic
70000069301•Cardinal Health
$0.0160
per ML
FT CHILD ALLERGY 12.5 MG/5 ML
Generic
70677101202•Strategic Sourcing Services LLC
$0.0160
per ML

Frequently asked questions

What is the NADAC price of M-DRYL 12.5 MG/5 ML SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for M-DRYL 12.5 MG/5 ML SOLUTION, manufactured by Method Pharmaceuticals LLC, is $0.0196 per ML (NDC 58657052804), effective Aug 19, 2026.

How has the price of M-DRYL 12.5 MG/5 ML SOLUTION changed over time?

Over the history we have for it, the NADAC for M-DRYL 12.5 MG/5 ML SOLUTION has declined 30.3%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for M-DRYL 12.5 MG/5 ML SOLUTION?

Since Apr 17, 2024, the NADAC for M-DRYL 12.5 MG/5 ML SOLUTION has ranged from a low of $0.0164 (Feb 12, 2025) to a high of $0.0282 (Jul 10, 2024), with a median of $0.0192 per ML.

Are there cheaper alternatives to M-DRYL 12.5 MG/5 ML SOLUTION?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, M-DRYL 12.5 MG/5 ML SOLUTION, is $0.0175 per ML — about 11% below M-DRYL 12.5 MG/5 ML SOLUTION.

Who manufactures M-DRYL 12.5 MG/5 ML SOLUTION?

M-DRYL 12.5 MG/5 ML SOLUTION (NDC 58657052804) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.