Product Information
M-DRYL 12.5 MG/5 ML SOLUTION is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.0170 per ML under NDC 58657052816. Its NADAC has been published 351 times since Oct 9, 2019.
Strength
12.5 mg/5mL
Manufacturer
Method Pharmaceuticals LLCNDC
58657052816
Classification
Generic
Dosage Form
LIQUID
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M012On Market Since
8/1/2019
Pharmacological Classes
Price Statistics
The NADAC for M-DRYL 12.5 MG/5 ML SOLUTION has been published 351 times since Oct 9, 2019, and over the history we have for it it has risen 154.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0170 per ML |
|---|---|
| All-time high | $0.0277 (Mar 11, 2020) |
| All-time low | $0.0067 (Oct 9, 2019) |
| 52-week high | $0.0178 |
| 52-week low | $0.0121 |
| Median price | $0.0159 |
| Average price | $0.0167 |
| Largest weekly change | +307.3% (Dec 18, 2019) |
| Weeks tracked | 351 |
| Tracking since | Oct 9, 2019 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of M-DRYL 12.5 MG/5 ML SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for M-DRYL 12.5 MG/5 ML SOLUTION, manufactured by Method Pharmaceuticals LLC, is $0.0170 per ML (NDC 58657052816), effective Jun 24, 2026.
How has the price of M-DRYL 12.5 MG/5 ML SOLUTION changed over time?
Over the history we have for it, the NADAC for M-DRYL 12.5 MG/5 ML SOLUTION has risen 154.4%. It has been tracked across 351 weekly CMS publications since Oct 9, 2019.
What are the highest and lowest recorded NADAC prices for M-DRYL 12.5 MG/5 ML SOLUTION?
Since Oct 9, 2019, the NADAC for M-DRYL 12.5 MG/5 ML SOLUTION has ranged from a low of $0.0067 (Oct 9, 2019) to a high of $0.0277 (Mar 11, 2020), with a median of $0.0159 per ML.
Are there cheaper alternatives to M-DRYL 12.5 MG/5 ML SOLUTION?
1 NADAC-published product shares the same active ingredient, strength, and dosage form as M-DRYL 12.5 MG/5 ML SOLUTION, but none are currently priced below it.
Who manufactures M-DRYL 12.5 MG/5 ML SOLUTION?
M-DRYL 12.5 MG/5 ML SOLUTION (NDC 58657052816) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.
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