Back to Market Feed

Product Information

M-DRYL 12.5 MG/5 ML SOLUTION is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.0175 per ML under NDC 58657052816. Its NADAC has been published 359 times since Oct 9, 2019.

M-DRYL 12.5 MG/5 ML SOLUTION

DIPHENHYDRAMINE HYDROCHLORIDE
$0.0175per ML
OTC

Strength

12.5 mg/5mL

NDC

58657052816

Classification

Generic

Dosage Form

LIQUID

Route

ORAL

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

8/1/2019

Pharmacological Classes

Histamine H1 Receptor Antagonists
Histamine-1 Receptor Antagonist

Price Statistics

The NADAC for M-DRYL 12.5 MG/5 ML SOLUTION has been published 359 times since Oct 9, 2019, and over the history we have for it it has risen 161.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0175 per ML
All-time high$0.0277 (Mar 11, 2020)
All-time low$0.0067 (Oct 9, 2019)
52-week high$0.0178
52-week low$0.0122
Median price$0.0163
Average price$0.0167
Largest weekly change+307.3% (Dec 18, 2019)
Weeks tracked359
Tracking sinceOct 9, 2019

Price History

1W

+3.2%

1M

+3.2%

3M

+2.2%

6M

+2.2%

1Y

+43.2%

3Y

+7.4%

5Y

-13.8%

All

+161.7%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

M-DRYL 12.5 MG/5 ML SOLUTION
Generic
58657052804•Method Pharmaceuticals LLC
$0.0196
+12% more

Related Drugs

Same classification

GS SLEEP TIME 50 MG/30 ML LIQ
Generic
00113018640•L. Perrigo Company
$0.0085
per ML
GNP SLEEP AID 50 MG/30 ML LIQ
Generic
46122075429•AmerisourceBergen
$0.0085
per ML
PV FLU RELIEF THERAPY LIQUID
Generic
68016015408•Chain Drug Marketing Association
$0.0121
per ML
QC EZZ NITE SLEEP 50 MG/30 ML
Generic
83324001506•Chain Drug Marketing Association
$0.0136
per ML
CHILD'S ALLERGY 12.5 MG/5 ML
Generic
36800037934•Topco Associates LLC
$0.0143
per ML
CHILD'S ALLERGY 12.5 MG/5 ML
Generic
36800037926•Topco Associates LLC
$0.0145
per ML
QC CHILD ALLERGY 12.5 MG/5 ML
Generic
63868037004•Chain Drug Marketing Association
$0.0155
per ML
QC CHILD ALLERGY 12.5 MG/5 ML
Generic
63868082354•Chain Drug Marketing Association
$0.0155
per ML
CHILD ALLERGY RLF 12.5 MG/5 ML
Generic
70000069301•Cardinal Health
$0.0160
per ML
FT CHILD ALLERGY 12.5 MG/5 ML
Generic
70677101202•Strategic Sourcing Services LLC
$0.0160
per ML

Frequently asked questions

What is the NADAC price of M-DRYL 12.5 MG/5 ML SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for M-DRYL 12.5 MG/5 ML SOLUTION, manufactured by Method Pharmaceuticals LLC, is $0.0175 per ML (NDC 58657052816), effective Aug 19, 2026.

How has the price of M-DRYL 12.5 MG/5 ML SOLUTION changed over time?

Over the history we have for it, the NADAC for M-DRYL 12.5 MG/5 ML SOLUTION has risen 161.7%. It has been tracked across 359 weekly CMS publications since Oct 9, 2019.

What are the highest and lowest recorded NADAC prices for M-DRYL 12.5 MG/5 ML SOLUTION?

Since Oct 9, 2019, the NADAC for M-DRYL 12.5 MG/5 ML SOLUTION has ranged from a low of $0.0067 (Oct 9, 2019) to a high of $0.0277 (Mar 11, 2020), with a median of $0.0163 per ML.

Are there cheaper alternatives to M-DRYL 12.5 MG/5 ML SOLUTION?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as M-DRYL 12.5 MG/5 ML SOLUTION in a comparable dosage form, but none are currently priced below it.

Who manufactures M-DRYL 12.5 MG/5 ML SOLUTION?

M-DRYL 12.5 MG/5 ML SOLUTION (NDC 58657052816) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.