Product Information

ROFLUMILAST 500 MCG TABLET is a generic product labeled by American Health Packaging, priced at $0.3160 per EA under NDC 60687078621. Its NADAC has been published 138 times since Jan 3, 2024.

FDA first approved this application on Nov 23, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ROFLUMILAST 500 MCG TABLET

Roflumilast
$0.3160per EA

Strength

500 ug/1

NDC

60687078621

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ROFLUMILAST

Approval Type

Generic (ANDA)

FDA Application

ANDA208213

FDA Approved

11/23/2018

TE Code

AB

On Market Since

12/7/2023

Pharmacological Classes

Phosphodiesterase 4 Inhibitor
Phosphodiesterase 4 Inhibitors

Price Statistics

The NADAC for ROFLUMILAST 500 MCG TABLET has been published 138 times since Jan 3, 2024, and over the history we have for it it has declined 20.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3160 per EA
All-time high$0.4359 (Apr 10, 2024)
All-time low$0.2563 (Nov 20, 2024)
52-week high$0.3458
52-week low$0.3118
Median price$0.3364
Average price$0.3453
Largest weekly change+40.4% (Jun 19, 2024)
Weeks tracked138
Tracking sinceJan 3, 2024

Price History

1W

+1.2%

1M

+1.2%

3M

-1.6%

6M

-3.1%

1Y

-8.6%

3Y

N/A

5Y

N/A

All

-20.4%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ROFLUMILAST 500 MCG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ROFLUMILAST 500 MCG TABLET, manufactured by American Health Packaging, is $0.3160 per EA (NDC 60687078621), effective Aug 19, 2026.

How has the price of ROFLUMILAST 500 MCG TABLET changed over time?

Over the history we have for it, the NADAC for ROFLUMILAST 500 MCG TABLET has declined 20.4%. It has been tracked across 138 weekly CMS publications since Jan 3, 2024.

What are the highest and lowest recorded NADAC prices for ROFLUMILAST 500 MCG TABLET?

Since Jan 3, 2024, the NADAC for ROFLUMILAST 500 MCG TABLET has ranged from a low of $0.2563 (Nov 20, 2024) to a high of $0.4359 (Apr 10, 2024), with a median of $0.3364 per EA.

Are there cheaper alternatives to ROFLUMILAST 500 MCG TABLET?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ROFLUMILAST 500 MCG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures ROFLUMILAST 500 MCG TABLET?

ROFLUMILAST 500 MCG TABLET (NDC 60687078621) is labeled by American Health Packaging, and CMS classifies it as a generic product.