This NDC is on FDA's drug shortage list (posted Oct 31, 2017)
Reported reason: Other
Product Information
HYDROMORPHONE 50 MG/5 ML VIAL is a generic product labeled by Fresenius Kabi USA, LLC, priced at $2.5663 per ML under NDC 63323085115. Its NADAC has been published 31 times since Jan 21, 2026.
FDA first approved this application on Jan 11, 1984. Its Orange Book therapeutic-equivalence code is AP.
Strength
10 mg/mL
Manufacturer
Fresenius Kabi USA, LLCNDC
63323085115
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Effective Date
5/20/2026
Active Ingredients
HYDROMORPHONE HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA019034FDA Approved
1/11/1984
TE Code
AP
On Market Since
12/15/2017
Pharmacological Classes
Price Statistics
The NADAC for HYDROMORPHONE 50 MG/5 ML VIAL has been published 31 times since Jan 21, 2026, and over the history we have for it it has risen 5.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.5663 per ML |
|---|---|
| All-time high | $2.5663 (Aug 19, 2026) |
| All-time low | $2.4402 (Jan 21, 2026) |
| 52-week high | $2.5663 |
| 52-week low | $2.4402 |
| Median price | $2.5663 |
| Average price | $2.5351 |
| Largest weekly change | +2.6% (Feb 18, 2026) |
| Weeks tracked | 31 |
| Tracking since | Jan 21, 2026 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROMORPHONE 50 MG/5 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for HYDROMORPHONE 50 MG/5 ML VIAL, manufactured by Fresenius Kabi USA, LLC, is $2.5663 per ML (NDC 63323085115), effective Aug 19, 2026.
How has the price of HYDROMORPHONE 50 MG/5 ML VIAL changed over time?
Over the history we have for it, the NADAC for HYDROMORPHONE 50 MG/5 ML VIAL has risen 5.2%. It has been tracked across 31 weekly CMS publications since Jan 21, 2026.
What are the highest and lowest recorded NADAC prices for HYDROMORPHONE 50 MG/5 ML VIAL?
Since Jan 21, 2026, the NADAC for HYDROMORPHONE 50 MG/5 ML VIAL has ranged from a low of $2.4402 (Jan 21, 2026) to a high of $2.5663 (Aug 19, 2026), with a median of $2.5663 per ML.
Are there cheaper alternatives to HYDROMORPHONE 50 MG/5 ML VIAL?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HYDROMORPHONE 50 MG/5 ML VIAL in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROMORPHONE 50 MG/5 ML VIAL?
HYDROMORPHONE 50 MG/5 ML VIAL (NDC 63323085115) is labeled by Fresenius Kabi USA, LLC, and CMS classifies it as a generic product.
Is HYDROMORPHONE 50 MG/5 ML VIAL in shortage?
Yes — NDC 63323085115 is currently listed in FDA's drug shortage database (posted Oct 31, 2017). Reported reason: Other.