Product Information

HYDROMORPHONE 500 MG/50 ML VL is a generic product labeled by Fresenius Kabi USA, LLC, priced at $2.5663 per ML under NDC 63323085150. Its NADAC has been published 23 times since Jan 21, 2026.

HYDROMORPHONE 500 MG/50 ML VL

Hydromorphone Hydrochloride
$2.5663per ML
DEA Schedule CII

Strength

10 mg/mL

NDC

63323085150

Classification

Generic

Dosage Form

INJECTION, SOLUTION

Route

INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS

Last Updated

5/20/2026

Active Ingredients

HYDROMORPHONE HYDROCHLORIDE

Approval Type

New Drug (NDA)

FDA Application

NDA019034

On Market Since

12/15/2017

Pharmacological Classes

Full Opioid Agonists
Opioid Agonist

Price Statistics

The NADAC for HYDROMORPHONE 500 MG/50 ML VL has been published 23 times since Jan 21, 2026, and over the history we have for it it has risen 5.2%. The table below summarizes its recorded NADAC range and movement.

Current price$2.5663 per ML
All-time high$2.5663 (Jun 24, 2026)
All-time low$2.4402 (Jan 21, 2026)
52-week high$2.5663
52-week low$2.4402
Median price$2.5242
Average price$2.5242
Largest weekly change+2.6% (Feb 18, 2026)
Weeks tracked23
Tracking sinceJan 21, 2026

Price History

1W

0.0%

1M

0.0%

3M

+1.7%

6M

N/A

1Y

N/A

3Y

N/A

5Y

N/A

All

+5.2%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of HYDROMORPHONE 500 MG/50 ML VL?

The current National Average Drug Acquisition Cost (NADAC) for HYDROMORPHONE 500 MG/50 ML VL, manufactured by Fresenius Kabi USA, LLC, is $2.5663 per ML (NDC 63323085150), effective Jun 24, 2026.

How has the price of HYDROMORPHONE 500 MG/50 ML VL changed over time?

Over the history we have for it, the NADAC for HYDROMORPHONE 500 MG/50 ML VL has risen 5.2%. It has been tracked across 23 weekly CMS publications since Jan 21, 2026.

What are the highest and lowest recorded NADAC prices for HYDROMORPHONE 500 MG/50 ML VL?

Since Jan 21, 2026, the NADAC for HYDROMORPHONE 500 MG/50 ML VL has ranged from a low of $2.4402 (Jan 21, 2026) to a high of $2.5663 (Jun 24, 2026), with a median of $2.5242 per ML.

Are there cheaper alternatives to HYDROMORPHONE 500 MG/50 ML VL?

2 NADAC-published products share the same active ingredient, strength, and dosage form as HYDROMORPHONE 500 MG/50 ML VL, but none are currently priced below it.

Who manufactures HYDROMORPHONE 500 MG/50 ML VL?

HYDROMORPHONE 500 MG/50 ML VL (NDC 63323085150) is labeled by Fresenius Kabi USA, LLC, and CMS classifies it as a generic product.