This NDC is on FDA's drug shortage list (posted Oct 31, 2017)
Product Information
HYDROMORPHONE 2 MG/ML VIAL is a generic product labeled by Fresenius Kabi USA, LLC, priced at $2.7403 per ML under NDC 63323085325. Its NADAC has been published 101 times since Sep 18, 2024.
FDA first approved this application on Jan 11, 1984. Its Orange Book therapeutic-equivalence code is AP.
Strength
2 mg/mL
Manufacturer
Fresenius Kabi USA, LLCNDC
63323085325
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Effective Date
7/22/2026
Active Ingredients
HYDROMORPHONE HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA019034FDA Approved
1/11/1984
TE Code
AP
On Market Since
12/15/2017
Pharmacological Classes
Price Statistics
The NADAC for HYDROMORPHONE 2 MG/ML VIAL has been published 101 times since Sep 18, 2024, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.7403 per ML |
|---|---|
| All-time high | $2.8038 (Jan 14, 2026) |
| All-time low | $2.7086 (Sep 18, 2024) |
| 52-week high | $2.8038 |
| 52-week low | $2.7230 |
| Median price | $2.7303 |
| Average price | $2.7414 |
| Largest weekly change | +1.4% (Oct 22, 2025) |
| Weeks tracked | 101 |
| Tracking since | Sep 18, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROMORPHONE 2 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for HYDROMORPHONE 2 MG/ML VIAL, manufactured by Fresenius Kabi USA, LLC, is $2.7403 per ML (NDC 63323085325), effective Aug 19, 2026.
How has the price of HYDROMORPHONE 2 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for HYDROMORPHONE 2 MG/ML VIAL has held within roughly two percent of its current level. It has been tracked across 101 weekly CMS publications since Sep 18, 2024.
What are the highest and lowest recorded NADAC prices for HYDROMORPHONE 2 MG/ML VIAL?
Since Sep 18, 2024, the NADAC for HYDROMORPHONE 2 MG/ML VIAL has ranged from a low of $2.7086 (Sep 18, 2024) to a high of $2.8038 (Jan 14, 2026), with a median of $2.7303 per ML.
Are there cheaper alternatives to HYDROMORPHONE 2 MG/ML VIAL?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as HYDROMORPHONE 2 MG/ML VIAL in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROMORPHONE 2 MG/ML VIAL?
HYDROMORPHONE 2 MG/ML VIAL (NDC 63323085325) is labeled by Fresenius Kabi USA, LLC, and CMS classifies it as a generic product.
Is HYDROMORPHONE 2 MG/ML VIAL in shortage?
Yes — NDC 63323085325 is currently listed in FDA's drug shortage database (posted Oct 31, 2017).