Drug Markets/Hydromorphone Hydrochloride

Hydromorphone Hydrochloride

41 NDCs across 11 manufacturers|37 Generic,4 Brand

Hydromorphone Hydrochloride is used to treat cough and postoperative pain, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved on Jan 11, 1984, and the first generic was approved Aug 23, 1995. FDA's Orange Book lists 24 AB-rated (therapeutically equivalent) products for this ingredient.

Hydromorphone Hydrochloride is available as 41 NDCs from 11 manufacturers (37 generic, 4 brand), with NADAC prices from $0.17 to $40.10 per EA — the most expensive product costs about 240× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Active FDA drug shortage

26 Hydromorphone Hydrochloride presentations are currently listed in FDA's drug shortage database (first posted Oct 31, 2017). Shortages can move NADAC prices in the following weeks.

Total NDCs

37G / 4B

Manufacturers

competing in market

Price Spread

$0.17 – $40.10

per EA, 29 of 41 NDCs

7d Activity

14↑11↓16 flat

avg -0.5% WoW · of 41 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

11 manufacturers producing HYDROMORPHONE HYDROCHLORIDE

Rhodes Pharmaceuticals L.P.

Trigen Laboratories, LLC

4 NDCs

$17.0027

avg/unit

Camber Pharmaceuticals Inc.

Fresenius Kabi USA, LLC

Hikma Pharmaceuticals USA Inc.

2 NDCs

$1.4884

avg/unit

Teva Parenteral Medicines, Inc.

2 NDCs

$2.5663

avg/unit

American Health Packaging

2 NDCs

$0.1920

avg/unit

Drug Portfolio

41 NDCs total, 41 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
HYDROMORPHONE HCL ER 32 MG TAB	00574029701	Padagis US LLC	$40.1024 per EA	High Outlier	Generic	—	Opioid Agonist
HYDROMORPHONE HCL ER 32 MG TAB	13811070410	Trigen Laboratories, LLC	$40.1024 per EA	High Outlier	Generic	—	Opioid Agonist
HYDROMORPHONE HCL ER 16 MG TAB	13811070310	Trigen Laboratories, LLC	$11.8168 per EA	High Outlier	Generic	+1.62%	Opioid Agonist
HYDROMORPHONE HCL ER 16 MG TAB	00574029501	Padagis US LLC	$11.8168 per EA	High Outlier	Generic	+1.62%	Opioid Agonist
HYDROMORPHONE HCL ER 16 MG TAB	31722012101	Camber Pharmaceuticals Inc.	$11.8168 per EA	—	Generic	+1.62%	Opioid Agonist
HYDROMORPHONE HCL ER 12 MG TAB	00574029401	Padagis US LLC	$10.2571 per EA	High Outlier	Generic	+0.65%	Opioid Agonist
HYDROMORPHONE HCL ER 12 MG TAB	13811070210	Trigen Laboratories, LLC	$10.2571 per EA	High Outlier	Generic	+0.65%	Opioid Agonist
HYDROMORPHONE HCL ER 12 MG TAB	31722012001	Camber Pharmaceuticals Inc.	$10.2571 per EA	—	Generic	+0.65%	Opioid Agonist
HYDROMORPHONE 3 MG SUPPOS	00574722406	Padagis US LLC	$9.5820 per EA	High Outlier	Generic	—	Opioid Agonist
DILAUDID 8 MG TABLET	42858033801	Rhodes Pharmaceuticals L.P.	$7.2381 per EA	—	Brand	—	Opioid Agonist
HYDROMORPHONE HCL ER 8 MG TAB	31722011901	Camber Pharmaceuticals Inc.	$5.8345 per EA	—	Generic	-4.56%	Opioid Agonist
HYDROMORPHONE HCL ER 8 MG TAB	00574029301	Padagis US LLC	$5.8345 per EA	High Outlier	Generic	-4.56%	Opioid Agonist
HYDROMORPHONE HCL ER 8 MG TAB	13811070110	Trigen Laboratories, LLC	$5.8345 per EA	High Outlier	Generic	-4.56%	Opioid Agonist
DILAUDID 4 MG TABLET	42858023450	Rhodes Pharmaceuticals L.P.	$3.9559 per EA	—	Brand	—	Opioid Agonist
DILAUDID 4 MG TABLET	42858023401	Rhodes Pharmaceuticals L.P.	$3.9559 per EA	—	Brand	—	Opioid Agonist
HYDROMORPHONE 2 MG/ML CARPUJCT	00409131230	Hospira Inc.	$3.2446 per ML	—	Generic	—	Opioid Agonist
HYDROMORPHONE 2 MG/ML VIAL	63323085325	Fresenius Kabi USA, LLC	$2.7403 per ML	—	Generic	—	Opioid Agonist
HYDROMORPHONE 2 MG/ML VIAL	00641615125	Hikma Pharmaceuticals USA Inc.	$2.7403 per ML	—	Generic	—	Opioid Agonist
HYDROMORPHONE 50 MG/5 ML VIAL	00409263405	Hospira Inc.	$2.5663 per ML	—	Generic	—	Opioid Agonist
HYDROMORPHONE 10 MG/ML VIAL	00703001801	Teva Parenteral Medicines, Inc.	$2.5663 per ML	—	Generic	—	Opioid Agonist
HYDROMORPHONE 500 MG/50 ML VIAL	00409263450	Hospira Inc.	$2.5663 per ML	—	Generic	—	Opioid Agonist
HYDROMORPHONE 500 MG/50 ML VL	63323085150	Fresenius Kabi USA, LLC	$2.5663 per ML	—	Generic	—	Opioid Agonist
HYDROMORPHONE 50 MG/5 ML VIAL	63323085115	Fresenius Kabi USA, LLC	$2.5663 per ML	—	Generic	—	Opioid Agonist
HYDROMORPHONE 50 MG/5 ML VIAL	00703011303	Teva Parenteral Medicines, Inc.	$2.5663 per ML	—	Generic	—	Opioid Agonist
DILAUDID 5 MG/5 ML ORAL LIQUID	42858041616	Rhodes Pharmaceuticals L.P.	$0.8521 per ML	—	Brand	—	Opioid Agonist
HYDROMORPHONE 8 MG TABLET	13107010901	Aurolife Pharma LLC	$0.5683 per EA	—	Generic	+0.11%	Opioid Agonist
HYDROMORPHONE 8 MG TABLET	42858030301	Rhodes Pharmaceuticals L.P.	$0.5683 per EA	—	Generic	+0.11%	Opioid Agonist
HYDROMORPHONE 8 MG TABLET	00406324901	SpecGx LLC	$0.5683 per EA	—	Generic	+0.11%	Opioid Agonist
HYDROMORPHONE 1 MG/ML SOLUTION	00054038663	Hikma Pharmaceuticals USA Inc.	$0.2364 per ML	—	Generic	-0.65%	Opioid Agonist
HYDROMORPHONE 5 MG/5 ML SOLN	42858030416	Rhodes Pharmaceuticals L.P.	$0.2364 per ML	—	Generic	-0.65%	Opioid Agonist
HYDROMORPHONE 4 MG TABLET	13107010801	Aurolife Pharma LLC	$0.2168 per EA	—	Generic	-1.21%	Opioid Agonist
HYDROMORPHONE 4 MG TABLET	60687059001	American Health Packaging	$0.2168 per EA	—	Generic	-1.21%	Opioid Agonist
HYDROMORPHONE 4 MG TABLET	42858030250	Rhodes Pharmaceuticals L.P.	$0.2168 per EA	—	Generic	-1.21%	Opioid Agonist
HYDROMORPHONE 4 MG TABLET	42858030225	Rhodes Pharmaceuticals L.P.	$0.2168 per EA	—	Generic	-1.21%	Opioid Agonist
HYDROMORPHONE 4 MG TABLET	42858030201	Rhodes Pharmaceuticals L.P.	$0.2168 per EA	—	Generic	-1.21%	Opioid Agonist
HYDROMORPHONE 4 MG TABLET	00406324401	SpecGx LLC	$0.2168 per EA	—	Generic	-1.21%	Opioid Agonist
HYDROMORPHONE 2 MG TABLET	00406324301	SpecGx LLC	$0.1671 per EA	—	Generic	+0.77%	Opioid Agonist
HYDROMORPHONE 2 MG TABLET	60687057901	American Health Packaging	$0.1671 per EA	—	Generic	+0.77%	Opioid Agonist
HYDROMORPHONE 2 MG TABLET	42858030125	Rhodes Pharmaceuticals L.P.	$0.1671 per EA	—	Generic	+0.77%	Opioid Agonist
HYDROMORPHONE 2 MG TABLET	13107010701	Aurolife Pharma LLC	$0.1671 per EA	—	Generic	+0.77%	Opioid Agonist
HYDROMORPHONE 2 MG TABLET	42858030101	Rhodes Pharmaceuticals L.P.	$0.1671 per EA	—	Generic	+0.77%	Opioid Agonist

Frequently Asked Questions

What is Hydromorphone Hydrochloride used to treat?

Hydromorphone Hydrochloride is used to treat cough and postoperative pain, per the National Library of Medicine's MED-RT classification.

When did Hydromorphone Hydrochloride become available as a generic?

FDA approved the first generic Hydromorphone Hydrochloride (ANDA) on Aug 23, 1995. The Orange Book currently lists 24 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

Is Hydromorphone Hydrochloride in shortage?

Yes — FDA's drug shortage database currently lists 26 Hydromorphone Hydrochloride presentations with status "Current", first posted Oct 31, 2017.

How many Hydromorphone Hydrochloride products are on the market?

The Hydromorphone Hydrochloride drug market contains 41 NDCs from 11 manufacturers — 37 generic and 4 brand products.

What is the price range for Hydromorphone Hydrochloride?

NADAC reference prices for Hydromorphone Hydrochloride range from $0.1671 to $40.1024 per EA — the most expensive product costs about 240× the cheapest. 12 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.

Is generic Hydromorphone Hydrochloride cheaper than brand?

The average generic NADAC for Hydromorphone Hydrochloride is $6.8213 per EA, versus $5.0500 for brand-labeled products — brand is currently about 26% cheaper on average.

Which manufacturers make Hydromorphone Hydrochloride?

11 manufacturers list Hydromorphone Hydrochloride in NADAC. Ranked by number of NDCs, the largest are Rhodes Pharmaceuticals L.P. (11), Padagis US LLC (5), Trigen Laboratories, LLC (4), Camber Pharmaceuticals Inc. (3), Hospira Inc. (3).

How has the price of Hydromorphone Hydrochloride changed recently?

Over the past 7 days, 14 Hydromorphone Hydrochloride NDCs rose and 11 fell, with a market-wide average change of -0.5%.