Product Information

KETOROLAC 0.5% OPHTH SOLUTION is a generic product labeled by Caplin Steriles Limited, priced at $1.4485 per ML under NDC 65145013901. Its NADAC has been published 67 times since May 14, 2025.

FDA first approved this application on Mar 26, 2024. Its Orange Book therapeutic-equivalence code is AT.

KETOROLAC 0.5% OPHTH SOLUTION

Ketorolac Tromethamine
$1.4485per ML

Strength

5 mg/mL

NDC

65145013901

Classification

Generic

Dosage Form

SOLUTION/ DROPS

Route

OPHTHALMIC

Effective Date

8/19/2026

Active Ingredients

KETOROLAC TROMETHAMINE

Approval Type

Generic (ANDA)

FDA Application

ANDA218204

FDA Approved

3/26/2024

TE Code

AT

On Market Since

1/23/2025

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Cyclooxygenase Inhibitor
Cyclooxygenase Inhibitors
Nonsteroidal Anti-inflammatory Drug

Price Statistics

The NADAC for KETOROLAC 0.5% OPHTH SOLUTION has been published 67 times since May 14, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.

Current price$1.4485 per ML
All-time high$1.5406 (Jan 14, 2026)
All-time low$1.3974 (Jun 18, 2025)
52-week high$1.5406
52-week low$1.3991
Median price$1.4474
Average price$1.4657
Largest weekly change+5.0% (Aug 20, 2025)
Weeks tracked67
Tracking sinceMay 14, 2025

Price History

1W

+0.1%

1M

+0.1%

3M

+3.5%

6M

-1.8%

1Y

-4.4%

3Y

N/A

5Y

N/A

All

-1.2%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 6% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of KETOROLAC 0.5% OPHTH SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for KETOROLAC 0.5% OPHTH SOLUTION, manufactured by Caplin Steriles Limited, is $1.4485 per ML (NDC 65145013901), effective Aug 19, 2026.

How has the price of KETOROLAC 0.5% OPHTH SOLUTION changed over time?

Over the history we have for it, the NADAC for KETOROLAC 0.5% OPHTH SOLUTION has held within roughly two percent of its current level. It has been tracked across 67 weekly CMS publications since May 14, 2025.

What are the highest and lowest recorded NADAC prices for KETOROLAC 0.5% OPHTH SOLUTION?

Since May 14, 2025, the NADAC for KETOROLAC 0.5% OPHTH SOLUTION has ranged from a low of $1.3974 (Jun 18, 2025) to a high of $1.5406 (Jan 14, 2026), with a median of $1.4474 per ML.

Are there cheaper alternatives to KETOROLAC 0.5% OPHTH SOLUTION?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, KETOROLAC 0.5% OPHTH SOLUTION, is $1.3575 per ML — about 6% below KETOROLAC 0.5% OPHTH SOLUTION.

Who manufactures KETOROLAC 0.5% OPHTH SOLUTION?

KETOROLAC 0.5% OPHTH SOLUTION (NDC 65145013901) is labeled by Caplin Steriles Limited, and CMS classifies it as a generic product.