Product Information

KETOROLAC 0.5% OPHTH SOLUTION is a generic product labeled by Caplin Steriles Limited, priced at $1.3575 per ML under NDC 65145014001. Its NADAC has been published 67 times since May 14, 2025.

FDA first approved this application on Mar 26, 2024. Its Orange Book therapeutic-equivalence code is AT.

KETOROLAC 0.5% OPHTH SOLUTION

Ketorolac Tromethamine
$1.3575per ML

Strength

5 mg/mL

NDC

65145014001

Classification

Generic

Dosage Form

SOLUTION/ DROPS

Route

OPHTHALMIC

Effective Date

8/19/2026

Active Ingredients

KETOROLAC TROMETHAMINE

Approval Type

Generic (ANDA)

FDA Application

ANDA218204

FDA Approved

3/26/2024

TE Code

AT

On Market Since

1/23/2025

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Cyclooxygenase Inhibitor
Cyclooxygenase Inhibitors
Nonsteroidal Anti-inflammatory Drug

Price Statistics

The NADAC for KETOROLAC 0.5% OPHTH SOLUTION has been published 67 times since May 14, 2025, and over the history we have for it it has risen 9.1%. The table below summarizes its recorded NADAC range and movement.

Current price$1.3575 per ML
All-time high$1.4384 (Sep 10, 2025)
All-time low$1.1713 (Mar 18, 2026)
52-week high$1.4384
52-week low$1.1713
Median price$1.2709
Average price$1.2822
Largest weekly change+12.2% (Aug 20, 2025)
Weeks tracked67
Tracking sinceMay 14, 2025

Price History

1W

+0.3%

1M

+0.3%

3M

+10.0%

6M

+14.0%

1Y

-5.6%

3Y

N/A

5Y

N/A

All

+9.1%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of KETOROLAC 0.5% OPHTH SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for KETOROLAC 0.5% OPHTH SOLUTION, manufactured by Caplin Steriles Limited, is $1.3575 per ML (NDC 65145014001), effective Aug 19, 2026.

How has the price of KETOROLAC 0.5% OPHTH SOLUTION changed over time?

Over the history we have for it, the NADAC for KETOROLAC 0.5% OPHTH SOLUTION has risen 9.1%. It has been tracked across 67 weekly CMS publications since May 14, 2025.

What are the highest and lowest recorded NADAC prices for KETOROLAC 0.5% OPHTH SOLUTION?

Since May 14, 2025, the NADAC for KETOROLAC 0.5% OPHTH SOLUTION has ranged from a low of $1.1713 (Mar 18, 2026) to a high of $1.4384 (Sep 10, 2025), with a median of $1.2709 per ML.

Are there cheaper alternatives to KETOROLAC 0.5% OPHTH SOLUTION?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as KETOROLAC 0.5% OPHTH SOLUTION in a comparable dosage form, but none are currently priced below it.

Who manufactures KETOROLAC 0.5% OPHTH SOLUTION?

KETOROLAC 0.5% OPHTH SOLUTION (NDC 65145014001) is labeled by Caplin Steriles Limited, and CMS classifies it as a generic product.