Drug Markets/Ketorolac Tromethamine

Ketorolac Tromethamine

71 NDCs across 29 manufacturers|68 Generic,3 Brand

Ketorolac Tromethamine is used to treat allergic conjunctivitis, inflammation, pain and photophobia, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved on Nov 30, 1989, and the first generic was approved May 16, 1997. FDA's Orange Book lists 8 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $37 million on Ketorolac Tromethamine across 1.7 million claims for 1.0 million beneficiaries.

Ketorolac Tromethamine is available as 71 NDCs from 29 manufacturers (68 generic, 3 brand), with NADAC prices from $0.50 to $54.45 per ML — the most expensive product costs about 109× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Active FDA drug shortage

25 Ketorolac Tromethamine presentations are currently listed in FDA's drug shortage database (first posted Mar 23, 2018). Shortages can move NADAC prices in the following weeks.

Total NDCs

68G / 3B

Manufacturers

competing in market

Price Spread

$0.50 – $54.45

per ML, 59 of 71 NDCs

7d Activity

34↑66↓-29 flat

avg +1.3% WoW · of 71 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Explore this market from other angles

Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.

Top supplier

Fresenius Kabi USA, LLC manufacturer profile

Open the supplier page for the manufacturer with the strongest footprint in this market.

Lead class

Cyclooxygenase Inhibitor class view

See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.

Trend hub

Latest market trends

Move from this single molecule into the current cross-market mover and volatility view.

Guide

How to interpret NADAC

Review the benchmark methodology behind the prices and spreads shown on this market page.

Manufacturer Breakdown

29 manufacturers producing KETOROLAC TROMETHAMINE(2 pricing outliers)

Fresenius Kabi USA, LLC

9 NDCs

$0.8386

avg/unit

Caplin Steriles Limited

5 NDCs

$1.0610

avg/unit

SOLA Pharmaceuticals LLC

Camber Pharmaceuticals Inc.

Sagent Pharmaceuticals

3 NDCs

$0.8386

avg/unit

Hikma Pharmaceuticals USA Inc.

3 NDCs

$0.9536

avg/unit

Alembic Pharmaceuticals Inc.

3 NDCs

$0.8386

avg/unit

Glenmark Pharmaceuticals Inc., USA

3 NDCs

$0.8386

avg/unit

Fosun Pharma USA Inc.

Sun Pharmaceutical Industries Inc.

1 NDC

$1.4749

avg/unit

Baxter Healthcare Corporation

American Health Packaging

Dr. Reddy's Laboratories Inc.

1 NDC

$0.1645

avg/unit

Ajanta Pharma USA Inc.

1 NDC

$0.1645

avg/unit

Mylan Pharmaceuticals Inc.

1 NDC

$0.1645

avg/unit

Zydus Pharmaceuticals (USA) Inc.

1 NDC

$0.1645

avg/unit

Major Pharmaceuticals

1 NDC

$0.1645

avg/unit

Teva Pharmaceuticals USA Inc.

Drug Portfolio

71 NDCs total, 71 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
ACULAR LS 0.4% OPHTH SOL	00023927705	Allergan, Inc.	$54.4550 per ML	High Outlier	Brand	-0.13%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
ACULAR 0.5% EYE DROPS	00023218105	Allergan, Inc.	$53.0952 per ML	High Outlier	Brand	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.4% OPHTH SOLUTION	60758077305	Pacific Pharma, Inc.	$12.6737 per ML	High Outlier	Generic	-0.29%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
ACUVAIL 0.45% OPHTH SOLUTION	00023350731	Allergan, Inc.	$10.7367 per EA	High Outlier	Brand	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	47335022090	Sun Pharmaceutical Industries Inc.	$1.4749 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	42571013725	Micro Labs Limited	$1.4508 per ML	—	Generic	+0.16%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	65145013901	Caplin Steriles Limited	$1.4508 per ML	—	Generic	+0.16%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	69315032205	Leading Pharma, LLC	$1.4508 per ML	—	Generic	+0.16%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	61314012605	Sandoz Inc.	$1.4508 per ML	—	Generic	+0.16%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	60505100301	Apotex Corp.	$1.4508 per ML	—	Generic	+0.16%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	70512079005	SOLA Pharmaceuticals LLC	$1.4508 per ML	—	Generic	+0.16%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	42571013726	Micro Labs Limited	$1.3384 per ML	—	Generic	-1.41%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	70512079010	SOLA Pharmaceuticals LLC	$1.3384 per ML	—	Generic	-1.41%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	60505100302	Apotex Corp.	$1.3384 per ML	—	Generic	-1.41%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	69315032210	Leading Pharma, LLC	$1.3384 per ML	—	Generic	-1.41%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	61314012610	Sandoz Inc.	$1.3384 per ML	—	Generic	-1.41%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 0.5% OPHTH SOLUTION	65145014001	Caplin Steriles Limited	$1.3384 per ML	—	Generic	-1.41%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	25021070101	Sagent Pharmaceuticals	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	65145014525	Caplin Steriles Limited	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	63323016212	Fresenius Kabi USA, LLC	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	00641604225	Hikma Pharmaceuticals USA Inc.	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	00409379501	Hospira Inc.	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	63323016216	Fresenius Kabi USA, LLC	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	00338007225	Baxter Healthcare Corporation	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	62332060025	Alembic Pharmaceuticals Inc.	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	68462075625	Glenmark Pharmaceuticals Inc., USA	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	70512084325	SOLA Pharmaceuticals LLC	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	63323016201	Fresenius Kabi USA, LLC	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	31722030625	Camber Pharmaceuticals Inc.	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	72266011825	Fosun Pharma USA Inc.	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	72572035525	Civica, Inc.	$1.0175 per ML	—	Generic	-2.61%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	25021070001	Sagent Pharmaceuticals	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	00409379325	Hospira Inc.	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	65145014625	Caplin Steriles Limited	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	70512084225	SOLA Pharmaceuticals LLC	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	63323016112	Fresenius Kabi USA, LLC	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	31722030525	Camber Pharmaceuticals Inc.	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	63323016116	Fresenius Kabi USA, LLC	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	00641604125	Hikma Pharmaceuticals USA Inc.	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	72603015325	NorthStar Rx LLC	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	00409379301	Hospira Inc.	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	62332059925	Alembic Pharmaceuticals Inc.	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	72266023425	Fosun Pharma USA Inc.	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	63323016101	Fresenius Kabi USA, LLC	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 15 MG/ML VIAL	68462075525	Glenmark Pharmaceuticals Inc., USA	$0.9459 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	00641604325	Hikma Pharmaceuticals USA Inc.	$0.8975 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 30 MG/ML VIAL	72603016125	NorthStar Rx LLC	$0.8790 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	25021070102	Sagent Pharmaceuticals	$0.5524 per ML	—	Generic	+10.91%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	31722030725	Camber Pharmaceuticals Inc.	$0.5524 per ML	—	Generic	+10.91%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	72266011925	Fosun Pharma USA Inc.	$0.5524 per ML	—	Generic	+10.91%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	00409379625	Hospira Inc.	$0.5524 per ML	—	Generic	+10.91%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	63323016226	Fresenius Kabi USA, LLC	$0.5524 per ML	—	Generic	+10.91%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	63323016214	Fresenius Kabi USA, LLC	$0.5524 per ML	—	Generic	+10.91%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	63323016202	Fresenius Kabi USA, LLC	$0.5524 per ML	—	Generic	+10.91%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	65145014725	Caplin Steriles Limited	$0.5524 per ML	—	Generic	+10.91%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	62332060125	Alembic Pharmaceuticals Inc.	$0.5524 per ML	—	Generic	+10.91%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	68462075725	Glenmark Pharmaceuticals Inc., USA	$0.5524 per ML	—	Generic	+10.91%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	70512084425	SOLA Pharmaceuticals LLC	$0.5524 per ML	—	Generic	+10.91%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	00409379601	Hospira Inc.	$0.4980 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 60 MG/2 ML VIAL	72603017225	NorthStar Rx LLC	$0.4980 per ML	—	Generic	—	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 10 MG TABLET	60687010421	American Health Packaging	$0.1645 per EA	—	Generic	-0.83%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 10 MG TABLET	69452027520	Bionpharma Inc.	$0.1645 per EA	—	Generic	-0.83%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 10 MG TABLET	43598013901	Dr. Reddy's Laboratories Inc.	$0.1645 per EA	—	Generic	-0.83%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 10 MG TABLET	27241031601	Ajanta Pharma USA Inc.	$0.1645 per EA	—	Generic	-0.83%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 10 MG TABLET	00378113401	Mylan Pharmaceuticals Inc.	$0.1645 per EA	—	Generic	-0.83%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 10 MG TABLET	70710171001	Zydus Pharmaceuticals (USA) Inc.	$0.1645 per EA	—	Generic	-0.83%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 10 MG TABLET	00904730304	Major Pharmaceuticals	$0.1645 per EA	—	Generic	-0.83%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 10 MG TABLET	31722068601	Camber Pharmaceuticals Inc.	$0.1645 per EA	—	Generic	-0.83%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 10 MG TABLET	69315026001	Leading Pharma, LLC	$0.1645 per EA	—	Generic	-0.83%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 10 MG TABLET	00093031401	Teva Pharmaceuticals USA Inc.	$0.1645 per EA	—	Generic	-0.83%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug
KETOROLAC 10 MG TABLET	62135081160	Chartwell RX LLC	$0.1645 per EA	—	Generic	-0.83%	Cyclooxygenase Inhibitor, Nonsteroidal Anti-inflammatory Drug

Frequently Asked Questions

What is Ketorolac Tromethamine used to treat?

Ketorolac Tromethamine is used to treat allergic conjunctivitis, inflammation, pain and photophobia, per the National Library of Medicine's MED-RT classification.

When did Ketorolac Tromethamine become available as a generic?

FDA approved the first generic Ketorolac Tromethamine (ANDA) on May 16, 1997. The Orange Book currently lists 8 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How much does Medicare spend on Ketorolac Tromethamine?

In 2024, Medicare Part D spent $37 million on Ketorolac Tromethamine across 1.7 million claims for 1.0 million beneficiaries.

Is Ketorolac Tromethamine in shortage?

Yes — FDA's drug shortage database currently lists 25 Ketorolac Tromethamine presentations with status "Current", first posted Mar 23, 2018.

How many Ketorolac Tromethamine products are on the market?

The Ketorolac Tromethamine drug market contains 71 NDCs from 29 manufacturers — 68 generic and 3 brand products.

What is the price range for Ketorolac Tromethamine?

NADAC reference prices for Ketorolac Tromethamine range from $0.4980 to $54.4550 per ML — the most expensive product costs about 109× the cheapest. 12 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.

Is generic Ketorolac Tromethamine cheaper than brand?

The average generic NADAC for Ketorolac Tromethamine is $1.1793 per ML, versus $53.7751 for brand-labeled products — brand versions average about 46× the generic price.

Which manufacturers make Ketorolac Tromethamine?

29 manufacturers list Ketorolac Tromethamine in NADAC. Ranked by number of NDCs, the largest are Fresenius Kabi USA, LLC (9), Caplin Steriles Limited (5), SOLA Pharmaceuticals LLC (5), Hospira Inc. (5), Camber Pharmaceuticals Inc. (4).

How has the price of Ketorolac Tromethamine changed recently?

Over the past 7 days, 34 Ketorolac Tromethamine NDCs rose and 66 fell, with a market-wide average change of +1.3%.