Product Information
NAPROXEN 500 MG TABLET is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.0580 per EA under NDC 65162019050. Its NADAC has been published 592 times since Apr 1, 2015.
FDA first approved this application on Dec 18, 2001. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162019050
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
NAPROXENApproval Type
Generic (ANDA)
FDA Application
ANDA075927FDA Approved
12/18/2001
TE Code
AB
On Market Since
2/18/2010
Pharmacological Classes
Price Statistics
The NADAC for NAPROXEN 500 MG TABLET has been published 592 times since Apr 1, 2015, and over the history we have for it it has risen 13.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0580 per EA |
|---|---|
| All-time high | $0.0874 (Aug 12, 2020) |
| All-time low | $0.0497 (Apr 17, 2024) |
| 52-week high | $0.0654 |
| 52-week low | $0.0580 |
| Median price | $0.0682 |
| Average price | $0.0682 |
| Largest weekly change | +33.6% (Jun 19, 2024) |
| Weeks tracked | 592 |
| Tracking since | Apr 1, 2015 |
Generic Alternatives
The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of NAPROXEN 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN 500 MG TABLET, manufactured by Amneal Pharmaceuticals LLC, is $0.0580 per EA (NDC 65162019050), effective Aug 19, 2026.
How has the price of NAPROXEN 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for NAPROXEN 500 MG TABLET has risen 13.1%. It has been tracked across 592 weekly CMS publications since Apr 1, 2015.
What are the highest and lowest recorded NADAC prices for NAPROXEN 500 MG TABLET?
Since Apr 1, 2015, the NADAC for NAPROXEN 500 MG TABLET has ranged from a low of $0.0497 (Apr 17, 2024) to a high of $0.0874 (Aug 12, 2020), with a median of $0.0682 per EA.
Are there cheaper alternatives to NAPROXEN 500 MG TABLET?
12 manufacturers publish a NADAC-priced product with the same active ingredient and strength as NAPROXEN 500 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures NAPROXEN 500 MG TABLET?
NAPROXEN 500 MG TABLET (NDC 65162019050) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.