Product Information
NAPROXEN DR 500 MG TABLET is a generic product labeled by Zameer Pharmaceuticals LLC, priced at $1.8643 per EA under NDC 90096016101. Its NADAC has been published 38 times since Dec 3, 2025.
FDA first approved this application on Oct 14, 1994. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Naproxen market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
500 mg/1
Manufacturer
Zameer Pharmaceuticals LLCNDC
90096016101
Classification
Generic
Dosage Form
TABLET, DELAYED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
NAPROXENApproval Type
Authorized Generic (NDA)
FDA Application
NDA020067FDA Approved
10/14/1994
TE Code
AB
On Market Since
8/31/2025
Pharmacological Classes
Price Statistics
The NADAC for NAPROXEN DR 500 MG TABLET has been published 38 times since Dec 3, 2025, and over the history we have for it it has declined 10.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.8643 per EA |
|---|---|
| All-time high | $2.0838 (Dec 10, 2025) |
| All-time low | $1.7881 (Mar 18, 2026) |
| 52-week high | $2.0838 |
| 52-week low | $1.7881 |
| Median price | $1.8709 |
| Average price | $1.8948 |
| Largest weekly change | -7.4% (Jan 21, 2026) |
| Weeks tracked | 38 |
| Tracking since | Dec 3, 2025 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 97% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of NAPROXEN DR 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN DR 500 MG TABLET, manufactured by Zameer Pharmaceuticals LLC, is $1.8643 per EA (NDC 90096016101), effective Aug 19, 2026.
How has the price of NAPROXEN DR 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for NAPROXEN DR 500 MG TABLET has declined 10.5%. It has been tracked across 38 weekly CMS publications since Dec 3, 2025.
What are the highest and lowest recorded NADAC prices for NAPROXEN DR 500 MG TABLET?
Since Dec 3, 2025, the NADAC for NAPROXEN DR 500 MG TABLET has ranged from a low of $1.7881 (Mar 18, 2026) to a high of $2.0838 (Dec 10, 2025), with a median of $1.8709 per EA.
Are there cheaper alternatives to NAPROXEN DR 500 MG TABLET?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, NAPROXEN 500 MG TABLET, is $0.0580 per EA — about 97% below NAPROXEN DR 500 MG TABLET.
Who manufactures NAPROXEN DR 500 MG TABLET?
NAPROXEN DR 500 MG TABLET (NDC 90096016101) is labeled by Zameer Pharmaceuticals LLC, and CMS classifies it as a generic product.