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Product Information

KETAMINE 500 MG/10 ML VIAL is a generic product labeled by Fresenius Kabi USA, LLC, priced at $0.5579 per ML under NDC 65219018810. Its NADAC has been published 36 times since Dec 17, 2025.

FDA first approved this application on Jan 13, 2023. Its Orange Book therapeutic-equivalence code is AP.

KETAMINE 500 MG/10 ML VIAL

ketamine hydrochloride
$0.5579per ML
DEA Schedule CIII

Strength

50 mg/mL

NDC

65219018810

Classification

Generic

Dosage Form

INJECTION

Route

INTRAMUSCULAR; INTRAVENOUS

Effective Date

8/19/2026

Active Ingredients

KETAMINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA215808

FDA Approved

1/13/2023

TE Code

AP

On Market Since

7/10/2023

Pharmacological Classes

General Anesthesia
General Anesthetic

Price Statistics

The NADAC for KETAMINE 500 MG/10 ML VIAL has been published 36 times since Dec 17, 2025, and over the history we have for it it has risen 4.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.5579 per ML
All-time high$0.5579 (Aug 19, 2026)
All-time low$0.5213 (Mar 18, 2026)
52-week high$0.5579
52-week low$0.5213
Median price$0.5331
Average price$0.5326
Largest weekly change+3.0% (Jun 17, 2026)
Weeks tracked36
Tracking sinceDec 17, 2025

Price History

1W

+1.2%

1M

+1.2%

3M

+6.5%

6M

+5.0%

1Y

N/A

3Y

N/A

5Y

N/A

All

+4.7%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the ketamine hydrochloride market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Related Drugs

Same classification

PROPOFOL 200 MG/20 ML VIAL
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$0.1709
per ML
PROPOFOL 200 MG/20 ML VIAL
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25021060820•Sagent Pharmaceuticals
$0.1709
per ML
PROPOFOL 200 MG/20 ML VIAL
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43598026525•Dr. Reddy's Laboratories Inc.
$0.1709
per ML
KETAMINE 500 MG/10 ML VIAL
Generic
00143950810•Hikma Pharmaceuticals USA Inc.
$0.5579
per ML
KETAMINE 500 MG/10 ML VIAL
Generic
00409205310•Hospira Inc.
$0.5579
per ML
KETAMINE 500 MG/10 ML VIAL
Generic
25021068310•Sagent Pharmaceuticals
$0.5579
per ML
KETAMINE 500 MG/10 ML VIAL
Generic
55150043910•Eugia US LLC
$0.5579
per ML
KETAMINE 500 MG/10 ML VIAL
Generic
72572032010•Civica, Inc.
$0.5579
per ML
KETAMINE 500 MG/5 ML VIAL
Generic
00143950910•Hikma Pharmaceuticals USA Inc.
$1.5436
per ML
KETAMINE 500 MG/5 ML VIAL
Generic
00409004010•Hospira Inc.
$1.5436
per ML

Frequently asked questions

What is the NADAC price of KETAMINE 500 MG/10 ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for KETAMINE 500 MG/10 ML VIAL, manufactured by Fresenius Kabi USA, LLC, is $0.5579 per ML (NDC 65219018810), effective Aug 19, 2026.

How has the price of KETAMINE 500 MG/10 ML VIAL changed over time?

Over the history we have for it, the NADAC for KETAMINE 500 MG/10 ML VIAL has risen 4.7%. It has been tracked across 36 weekly CMS publications since Dec 17, 2025.

What are the highest and lowest recorded NADAC prices for KETAMINE 500 MG/10 ML VIAL?

Since Dec 17, 2025, the NADAC for KETAMINE 500 MG/10 ML VIAL has ranged from a low of $0.5213 (Mar 18, 2026) to a high of $0.5579 (Aug 19, 2026), with a median of $0.5331 per ML.

Are there cheaper alternatives to KETAMINE 500 MG/10 ML VIAL?

No other NADAC-published product currently shares the active ingredient and strength of KETAMINE 500 MG/10 ML VIAL in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures KETAMINE 500 MG/10 ML VIAL?

KETAMINE 500 MG/10 ML VIAL (NDC 65219018810) is labeled by Fresenius Kabi USA, LLC, and CMS classifies it as a generic product.