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Product Information

KETAMINE 500 MG/10 ML VIAL is a generic product labeled by Sagent Pharmaceuticals, priced at $0.5579 per ML under NDC 25021068310. Its NADAC has been published 36 times since Dec 17, 2025.

FDA first approved this application on Jan 24, 2023. Its Orange Book therapeutic-equivalence code is AP.

KETAMINE 500 MG/10 ML VIAL

Ketamine Hydrochloride
$0.5579per ML
DEA Schedule CIII

Strength

50 mg/mL

NDC

25021068310

Classification

Generic

Dosage Form

INJECTION, SOLUTION

Route

INTRAMUSCULAR; INTRAVENOUS

Effective Date

8/19/2026

Active Ingredients

KETAMINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA216809

FDA Approved

1/24/2023

TE Code

AP

On Market Since

7/15/2023

Pharmacological Classes

General Anesthesia
General Anesthetic

Price Statistics

The NADAC for KETAMINE 500 MG/10 ML VIAL has been published 36 times since Dec 17, 2025, and over the history we have for it it has risen 4.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.5579 per ML
All-time high$0.5579 (Aug 19, 2026)
All-time low$0.5213 (Mar 18, 2026)
52-week high$0.5579
52-week low$0.5213
Median price$0.5331
Average price$0.5326
Largest weekly change+3.0% (Jun 17, 2026)
Weeks tracked36
Tracking sinceDec 17, 2025

Price History

1W

+1.2%

1M

+1.2%

3M

+6.5%

6M

+5.0%

1Y

N/A

3Y

N/A

5Y

N/A

All

+4.7%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

3 alternatives • Same active ingredient

KETAMINE 500 MG/10 ML VIAL
Generic
72572032010•Civica, Inc.
$0.5579
KETAMINE 500 MG/10 ML VIAL
Generic
00143950810•Hikma Pharmaceuticals USA Inc.
$0.5579
KETAMINE 500 MG/10 ML VIAL
Generic
00409205310•Hospira Inc.
$0.5579

Related Drugs

Same classification

PROPOFOL 200 MG/20 ML VIAL
Generic
00409601025•Hospira Inc.
$0.1709
per ML
PROPOFOL 200 MG/20 ML VIAL
Generic
25021060820•Sagent Pharmaceuticals
$0.1709
per ML
PROPOFOL 200 MG/20 ML VIAL
Generic
43598026525•Dr. Reddy's Laboratories Inc.
$0.1709
per ML
KETAMINE 500 MG/10 ML VIAL
Generic
55150043910•Eugia US LLC
$0.5579
per ML
KETAMINE 500 MG/10 ML VIAL
Generic
65219018810•Fresenius Kabi USA, LLC
$0.5579
per ML
KETAMINE 500 MG/5 ML VIAL
Generic
00409004010•Hospira Inc.
$1.5436
per ML
KETAMINE 500 MG/5 ML VIAL
Generic
65219018605•Fresenius Kabi USA, LLC
$1.5436
per ML

Frequently asked questions

What is the NADAC price of KETAMINE 500 MG/10 ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for KETAMINE 500 MG/10 ML VIAL, manufactured by Sagent Pharmaceuticals, is $0.5579 per ML (NDC 25021068310), effective Aug 19, 2026.

How has the price of KETAMINE 500 MG/10 ML VIAL changed over time?

Over the history we have for it, the NADAC for KETAMINE 500 MG/10 ML VIAL has risen 4.7%. It has been tracked across 36 weekly CMS publications since Dec 17, 2025.

What are the highest and lowest recorded NADAC prices for KETAMINE 500 MG/10 ML VIAL?

Since Dec 17, 2025, the NADAC for KETAMINE 500 MG/10 ML VIAL has ranged from a low of $0.5213 (Mar 18, 2026) to a high of $0.5579 (Aug 19, 2026), with a median of $0.5331 per ML.

Are there cheaper alternatives to KETAMINE 500 MG/10 ML VIAL?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as KETAMINE 500 MG/10 ML VIAL in a comparable dosage form, but none are currently priced below it.

Who manufactures KETAMINE 500 MG/10 ML VIAL?

KETAMINE 500 MG/10 ML VIAL (NDC 25021068310) is labeled by Sagent Pharmaceuticals, and CMS classifies it as a generic product.