Product Information
KETAMINE 500 MG/10 ML VIAL is a generic product labeled by Hospira Inc., priced at $0.5563 per ML under NDC 00409205310. Its NADAC has been published 42 times since Dec 17, 2025.
FDA first approved this application on Jun 27, 1996. Its Orange Book therapeutic-equivalence code is AP.
The High Outlier badge above means this manufacturer's average price in the Ketamine Hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 mg/mL
Manufacturer
Hospira Inc.NDC
00409205310
Classification
Generic
Dosage Form
INJECTION, SOLUTION, CONCENTRATE
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
9/23/2026
Active Ingredients
KETAMINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA074549FDA Approved
6/27/1996
TE Code
AP
On Market Since
11/30/2004
Pharmacological Classes
Price Statistics
The NADAC for KETAMINE 500 MG/10 ML VIAL has been published 42 times since Dec 17, 2025, and over the history we have for it it has risen 4.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5563 per ML |
|---|---|
| All-time high | $0.5579 (Sep 16, 2026) |
| All-time low | $0.5213 (Mar 18, 2026) |
| 52-week high | $0.5579 |
| 52-week low | $0.5213 |
| Median price | $0.5331 |
| Average price | $0.5361 |
| Largest weekly change | +3.0% (Jun 17, 2026) |
| Weeks tracked | 42 |
| Tracking since | Dec 17, 2025 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Hospira Inc. manufacturer profile
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Drug market
Ketamine Hydrochloride market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
General Anesthetic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of KETAMINE 500 MG/10 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for KETAMINE 500 MG/10 ML VIAL, manufactured by Hospira Inc., is $0.5563 per ML (NDC 00409205310), effective Sep 30, 2026.
How has the price of KETAMINE 500 MG/10 ML VIAL changed over time?
Over the history we have for it, the NADAC for KETAMINE 500 MG/10 ML VIAL has risen 4.4%. It has been tracked across 42 weekly CMS publications since Dec 17, 2025.
What are the highest and lowest recorded NADAC prices for KETAMINE 500 MG/10 ML VIAL?
Since Dec 17, 2025, the NADAC for KETAMINE 500 MG/10 ML VIAL has ranged from a low of $0.5213 (Mar 18, 2026) to a high of $0.5579 (Sep 16, 2026), with a median of $0.5331 per ML.
Are there cheaper alternatives to KETAMINE 500 MG/10 ML VIAL?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as KETAMINE 500 MG/10 ML VIAL in a comparable dosage form, but none are currently priced below it.
Who manufactures KETAMINE 500 MG/10 ML VIAL?
KETAMINE 500 MG/10 ML VIAL (NDC 00409205310) is labeled by Hospira Inc., and CMS classifies it as a generic product.