Product Information
EPHEDRINE SULFATE 50 MG/ML VL is a generic product labeled by Fresenius Kabi USA, LLC, priced at $5.6366 per ML under NDC 65219025701. Its NADAC has been published 61 times since Jul 17, 2024.
FDA first approved this application on Aug 4, 2020. Its Orange Book therapeutic-equivalence code is AP.
Strength
50 mg/mL
Manufacturer
Fresenius Kabi USA, LLCNDC
65219025701
Classification
Generic
Dosage Form
INJECTION
Route
INTRAVENOUS
Effective Date
9/18/2024
Active Ingredients
EPHEDRINE SULFATEApproval Type
Generic (ANDA)
FDA Application
ANDA209646FDA Approved
8/4/2020
TE Code
AP
On Market Since
10/31/2020
Pharmacological Classes
Price Statistics
The NADAC for EPHEDRINE SULFATE 50 MG/ML VL has been published 61 times since Jul 17, 2024, and over the history we have for it it has risen 2.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $5.6366 per ML |
|---|---|
| All-time high | $5.6366 (Sep 10, 2025) |
| All-time low | $5.4758 (Jul 17, 2024) |
| 52-week high | $5.6366 |
| 52-week low | $5.6366 |
| Median price | $5.6366 |
| Average price | $5.6235 |
| Largest weekly change | +2.9% (Aug 21, 2024) |
| Weeks tracked | 61 |
| Tracking since | Jul 17, 2024 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
N/A
5Y
N/A
All
+2.9%
Last surveyed Sep 10, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of EPHEDRINE SULFATE 50 MG/ML VL?
The current National Average Drug Acquisition Cost (NADAC) for EPHEDRINE SULFATE 50 MG/ML VL, manufactured by Fresenius Kabi USA, LLC, is $5.6366 per ML (NDC 65219025701), effective Sep 10, 2025.
How has the price of EPHEDRINE SULFATE 50 MG/ML VL changed over time?
Over the history we have for it, the NADAC for EPHEDRINE SULFATE 50 MG/ML VL has risen 2.9%. It has been tracked across 61 weekly CMS publications since Jul 17, 2024.
What are the highest and lowest recorded NADAC prices for EPHEDRINE SULFATE 50 MG/ML VL?
Since Jul 17, 2024, the NADAC for EPHEDRINE SULFATE 50 MG/ML VL has ranged from a low of $5.4758 (Jul 17, 2024) to a high of $5.6366 (Sep 10, 2025), with a median of $5.6366 per ML.
Are there cheaper alternatives to EPHEDRINE SULFATE 50 MG/ML VL?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, EPHEDRINE SULFATE 50 MG/ML VL, is $5.4758 per ML — about 3% below EPHEDRINE SULFATE 50 MG/ML VL.
Who manufactures EPHEDRINE SULFATE 50 MG/ML VL?
EPHEDRINE SULFATE 50 MG/ML VL (NDC 65219025701) is labeled by Fresenius Kabi USA, LLC, and CMS classifies it as a generic product.