Product Information
GLYBURID-METFORMIN 1.25-250 MG is a generic product labeled by Aurobindo Pharma Limited, priced at $0.0335 per EA under NDC 65862008001. Its NADAC has been published 459 times since Nov 28, 2013.
FDA first approved this application on Nov 14, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1.25; 250 mg/1; mg/1
Manufacturer
Aurobindo Pharma LimitedNDC
65862008001
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
12/18/2024
Active Ingredients
GLYBURIDE; METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA077870FDA Approved
11/14/2007
TE Code
AB
On Market Since
11/14/2007
Pharmacological Classes
Price Statistics
The NADAC for GLYBURID-METFORMIN 1.25-250 MG has been published 459 times since Nov 28, 2013, and over the history we have for it it has declined 61.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0335 per EA |
|---|---|
| All-time high | $0.0908 (May 11, 2016) |
| All-time low | $0.0335 (Oct 23, 2024) |
| 52-week high | $0.0335 |
| 52-week low | $0.0335 |
| Median price | $0.0529 |
| Average price | $0.0570 |
| Largest weekly change | +37.5% (Jun 22, 2016) |
| Weeks tracked | 459 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
-23.7%
5Y
-28.1%
All
-61.7%
Last surveyed Dec 10, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of GLYBURID-METFORMIN 1.25-250 MG?
The current National Average Drug Acquisition Cost (NADAC) for GLYBURID-METFORMIN 1.25-250 MG, manufactured by Aurobindo Pharma Limited, is $0.0335 per EA (NDC 65862008001), effective Dec 10, 2025.
How has the price of GLYBURID-METFORMIN 1.25-250 MG changed over time?
Over the history we have for it, the NADAC for GLYBURID-METFORMIN 1.25-250 MG has declined 61.7%. It has been tracked across 459 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for GLYBURID-METFORMIN 1.25-250 MG?
Since Nov 28, 2013, the NADAC for GLYBURID-METFORMIN 1.25-250 MG has ranged from a low of $0.0335 (Oct 23, 2024) to a high of $0.0908 (May 11, 2016), with a median of $0.0529 per EA.
Are there cheaper alternatives to GLYBURID-METFORMIN 1.25-250 MG?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as GLYBURID-METFORMIN 1.25-250 MG in a comparable dosage form, but none are currently priced below it.
Who manufactures GLYBURID-METFORMIN 1.25-250 MG?
GLYBURID-METFORMIN 1.25-250 MG (NDC 65862008001) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.