Product Information
GLYBURIDE-METFORMIN 5-500 MG is a generic product labeled by Aurobindo Pharma Limited, priced at $0.1896 per EA under NDC 65862008205. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Nov 14, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5; 500 mg/1; mg/1
Manufacturer
Aurobindo Pharma LimitedNDC
65862008205
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
GLYBURIDE; METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA077870FDA Approved
11/14/2007
TE Code
AB
On Market Since
11/14/2007
Pharmacological Classes
Price Statistics
The NADAC for GLYBURIDE-METFORMIN 5-500 MG has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 145.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1896 per EA |
|---|---|
| All-time high | $0.2013 (Jan 14, 2026) |
| All-time low | $0.0433 (Apr 17, 2024) |
| 52-week high | $0.2013 |
| 52-week low | $0.1804 |
| Median price | $0.0573 |
| Average price | $0.0765 |
| Largest weekly change | +83.1% (Dec 18, 2024) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Aurobindo Pharma Limited manufacturer profile
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Drug market
Glyburide and Metformin Hydrochloride market comparison
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Therapeutic class
Biguanide class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of GLYBURIDE-METFORMIN 5-500 MG?
The current National Average Drug Acquisition Cost (NADAC) for GLYBURIDE-METFORMIN 5-500 MG, manufactured by Aurobindo Pharma Limited, is $0.1896 per EA (NDC 65862008205), effective Sep 30, 2026.
How has the price of GLYBURIDE-METFORMIN 5-500 MG changed over time?
Over the history we have for it, the NADAC for GLYBURIDE-METFORMIN 5-500 MG has risen 145.9%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for GLYBURIDE-METFORMIN 5-500 MG?
Since Nov 28, 2013, the NADAC for GLYBURIDE-METFORMIN 5-500 MG has ranged from a low of $0.0433 (Apr 17, 2024) to a high of $0.2013 (Jan 14, 2026), with a median of $0.0573 per EA.
Are there cheaper alternatives to GLYBURIDE-METFORMIN 5-500 MG?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as GLYBURIDE-METFORMIN 5-500 MG in a comparable dosage form, but none are currently priced below it.
Who manufactures GLYBURIDE-METFORMIN 5-500 MG?
GLYBURIDE-METFORMIN 5-500 MG (NDC 65862008205) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.