Product Information

ALPRAZOLAM ER 0.5 MG TABLET is a generic product labeled by Aurobindo Pharma Limited, priced at $0.1483 per EA under NDC 65862045460. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Jun 7, 2011. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ALPRAZOLAM ER 0.5 MG TABLET

Alprazolam
$0.1483per EA
DEA Schedule CIV

Strength

.5 mg/1

NDC

65862045460

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ALPRAZOLAM

Approval Type

Generic (ANDA)

FDA Application

ANDA090871

FDA Approved

6/7/2011

TE Code

AB

On Market Since

6/7/2011

Pharmacological Classes

Benzodiazepine
Benzodiazepines

Price Statistics

The NADAC for ALPRAZOLAM ER 0.5 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 51.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1483 per EA
All-time high$0.3715 (Feb 12, 2014)
All-time low$0.1195 (Jun 17, 2020)
52-week high$0.1746
52-week low$0.1483
Median price$0.1945
Average price$0.2213
Largest weekly change+38.7% (Jul 22, 2020)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-4.5%

1M

-4.5%

3M

-7.0%

6M

-6.2%

1Y

-15.1%

3Y

-14.0%

5Y

-7.2%

All

-51.6%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 85% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ALPRAZOLAM ER 0.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ALPRAZOLAM ER 0.5 MG TABLET, manufactured by Aurobindo Pharma Limited, is $0.1483 per EA (NDC 65862045460), effective Aug 19, 2026.

How has the price of ALPRAZOLAM ER 0.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for ALPRAZOLAM ER 0.5 MG TABLET has declined 51.6%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ALPRAZOLAM ER 0.5 MG TABLET?

Since Nov 28, 2013, the NADAC for ALPRAZOLAM ER 0.5 MG TABLET has ranged from a low of $0.1195 (Jun 17, 2020) to a high of $0.3715 (Feb 12, 2014), with a median of $0.1945 per EA.

Are there cheaper alternatives to ALPRAZOLAM ER 0.5 MG TABLET?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ALPRAZOLAM 0.5 MG TABLET, is $0.0223 per EA — about 85% below ALPRAZOLAM ER 0.5 MG TABLET.

Who manufactures ALPRAZOLAM ER 0.5 MG TABLET?

ALPRAZOLAM ER 0.5 MG TABLET (NDC 65862045460) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.