Product Information

AZOPT 1% EYE DROPS is a brand product labeled by Sandoz Inc., priced at $35.2653 per ML under NDC 66758008585. Its NADAC has been published 82 times since Jan 29, 2025.

FDA first approved this application on Apr 1, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

AZOPT 1% EYE DROPS

brinzolamide
$35.2653per ML

Strength

10 mg/mL

Manufacturer

Sandoz Inc.

NDC

66758008585

Classification

Brand

Dosage Form

SUSPENSION/ DROPS

Route

OPHTHALMIC

Effective Date

8/19/2026

Active Ingredients

BRINZOLAMIDE

Approval Type

New Drug (NDA)

FDA Application

NDA020816

FDA Approved

4/1/1998

TE Code

AB

On Market Since

4/30/1998

Pharmacological Classes

Carbonic Anhydrase Inhibitor
Carbonic Anhydrase Inhibitors

Price Statistics

The NADAC for AZOPT 1% EYE DROPS has been published 82 times since Jan 29, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.

Current price$35.2653 per ML
All-time high$35.3114 (Feb 12, 2025)
All-time low$35.1601 (Oct 22, 2025)
52-week high$35.2653
52-week low$35.1601
Median price$35.2328
Average price$35.2356
Largest weekly change-0.3% (Oct 22, 2025)
Weeks tracked82
Tracking sinceJan 29, 2025

Price History

1W

+0.2%

1M

+0.2%

3M

+0.2%

6M

+0.2%

1Y

+0.0%

3Y

N/A

5Y

N/A

All

-0.1%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 73% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of AZOPT 1% EYE DROPS?

The current National Average Drug Acquisition Cost (NADAC) for AZOPT 1% EYE DROPS, manufactured by Sandoz Inc., is $35.2653 per ML (NDC 66758008585), effective Aug 19, 2026.

How has the price of AZOPT 1% EYE DROPS changed over time?

Over the history we have for it, the NADAC for AZOPT 1% EYE DROPS has held within roughly two percent of its current level. It has been tracked across 82 weekly CMS publications since Jan 29, 2025.

What are the highest and lowest recorded NADAC prices for AZOPT 1% EYE DROPS?

Since Jan 29, 2025, the NADAC for AZOPT 1% EYE DROPS has ranged from a low of $35.1601 (Oct 22, 2025) to a high of $35.3114 (Feb 12, 2025), with a median of $35.2328 per ML.

Are there cheaper alternatives to AZOPT 1% EYE DROPS?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BRINZOLAMIDE 1% EYE DROPS, is $9.4893 per ML — about 73% below AZOPT 1% EYE DROPS.

Who manufactures AZOPT 1% EYE DROPS?

AZOPT 1% EYE DROPS (NDC 66758008585) is labeled by Sandoz Inc., and CMS classifies it as a brand product.