Product Information

DIPHENHYDRAMINE 500 MG/10 ML VL is a generic product labeled by Mylan Institutional LLC, priced at $0.7900 per ML under NDC 67457012410. Its NADAC has been published 87 times since Aug 19, 2020.

DIPHENHYDRAMINE 500 MG/10 ML VL

diphenhydramine hydrochloride
$0.7900per ML
Discontinued

Strength

50 mg/mL

NDC

67457012410

Classification

Generic

Dosage Form

INJECTION, SOLUTION

Route

INTRAMUSCULAR; INTRAVENOUS

Last Updated

3/19/2025

Approval Type

Generic (ANDA)

FDA Application

ANDA040498

On Market Since

5/9/2013

Pharmacological Classes

Histamine H1 Receptor Antagonists
Histamine-1 Receptor Antagonist

Price Statistics

The NADAC for DIPHENHYDRAMINE 500 MG/10 ML VL has been published 87 times since Aug 19, 2020, and over the history we have for it it has risen 599.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.7900 per ML
All-time high$0.7900 (Feb 25, 2026)
All-time low$0.1129 (Aug 19, 2020)
52-week high$0.7900
52-week low$0.7900
Median price$0.7900
Average price$0.7689
Largest weekly change+583.0% (Jul 17, 2024)
Weeks tracked87
Tracking sinceAug 19, 2020

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

0.0%

3Y

+599.4%

5Y

+599.4%

All

+599.4%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIPHENHYDRAMINE 500 MG/10 ML VL?

The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 500 MG/10 ML VL, manufactured by Mylan Institutional LLC, is $0.7900 per ML (NDC 67457012410), effective Feb 25, 2026.

How has the price of DIPHENHYDRAMINE 500 MG/10 ML VL changed over time?

Over the history we have for it, the NADAC for DIPHENHYDRAMINE 500 MG/10 ML VL has risen 599.4%. It has been tracked across 87 weekly CMS publications since Aug 19, 2020.

What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 500 MG/10 ML VL?

Since Aug 19, 2020, the NADAC for DIPHENHYDRAMINE 500 MG/10 ML VL has ranged from a low of $0.1129 (Aug 19, 2020) to a high of $0.7900 (Feb 25, 2026), with a median of $0.7900 per ML.

Are there cheaper alternatives to DIPHENHYDRAMINE 500 MG/10 ML VL?

1 NADAC-published product shares the same active ingredient, strength, and dosage form as DIPHENHYDRAMINE 500 MG/10 ML VL, but none are currently priced below it.

Who manufactures DIPHENHYDRAMINE 500 MG/10 ML VL?

DIPHENHYDRAMINE 500 MG/10 ML VL (NDC 67457012410) is labeled by Mylan Institutional LLC, and CMS classifies it as a generic product.