Product Information

DIPHENHYDRAMINE 50 MG/ML VIAL is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $0.9399 per ML under NDC 00641037625. Its NADAC has been published 640 times since Nov 28, 2013.

DIPHENHYDRAMINE 50 MG/ML VIAL

diphenhydramine hydrochloride
$0.9399per ML

Strength

50 mg/mL

NDC

00641037625

Classification

Generic

Dosage Form

INJECTION

Route

INTRAMUSCULAR; INTRAVENOUS

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA080817

On Market Since

11/27/1972

Pharmacological Classes

Histamine H1 Receptor Antagonists
Histamine-1 Receptor Antagonist

Price Statistics

The NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has been published 640 times since Nov 28, 2013, and over the history we have for it it has risen 20.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.9399 per ML
All-time high$1.4470 (Apr 14, 2021)
All-time low$0.6403 (Jul 18, 2018)
52-week high$0.9459
52-week low$0.8905
Median price$0.8602
Average price$0.8687
Largest weekly change+51.1% (May 20, 2020)
Weeks tracked640
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

+0.3%

3M

-0.5%

6M

-0.2%

1Y

+1.3%

3Y

+0.1%

5Y

+1.1%

All

+20.4%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 16% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIPHENHYDRAMINE 50 MG/ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 50 MG/ML VIAL, manufactured by Hikma Pharmaceuticals USA Inc., is $0.9399 per ML (NDC 00641037625), effective Jun 24, 2026.

How has the price of DIPHENHYDRAMINE 50 MG/ML VIAL changed over time?

Over the history we have for it, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has risen 20.4%. It has been tracked across 640 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 50 MG/ML VIAL?

Since Nov 28, 2013, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has ranged from a low of $0.6403 (Jul 18, 2018) to a high of $1.4470 (Apr 14, 2021), with a median of $0.8602 per ML.

Are there cheaper alternatives to DIPHENHYDRAMINE 50 MG/ML VIAL?

Yes. 2 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, DIPHENHYDRAMINE 500 MG/10 ML VL, is $0.7900 per ML — about 16% below DIPHENHYDRAMINE 50 MG/ML VIAL.

Who manufactures DIPHENHYDRAMINE 50 MG/ML VIAL?

DIPHENHYDRAMINE 50 MG/ML VIAL (NDC 00641037625) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.