Product Information
DIPHENHYDRAMINE 50 MG/ML VIAL is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $0.9336 per ML under NDC 00641037625. Its NADAC has been published 648 times since Nov 28, 2013.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AP.
Strength
50 mg/mL
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00641037625
Classification
Generic
Dosage Form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
8/19/2026
Active Ingredients
DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA080817FDA Approved
Before 1982
TE Code
AP
On Market Since
11/27/1972
Pharmacological Classes
Price Statistics
The NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has been published 648 times since Nov 28, 2013, and over the history we have for it it has risen 19.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.9336 per ML |
|---|---|
| All-time high | $1.4470 (Apr 14, 2021) |
| All-time low | $0.6403 (Jul 18, 2018) |
| 52-week high | $0.9459 |
| 52-week low | $0.8905 |
| Median price | $0.8627 |
| Average price | $0.8696 |
| Largest weekly change | +51.1% (May 20, 2020) |
| Weeks tracked | 648 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 15% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIPHENHYDRAMINE 50 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 50 MG/ML VIAL, manufactured by Hikma Pharmaceuticals USA Inc., is $0.9336 per ML (NDC 00641037625), effective Aug 19, 2026.
How has the price of DIPHENHYDRAMINE 50 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has risen 19.6%. It has been tracked across 648 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 50 MG/ML VIAL?
Since Nov 28, 2013, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has ranged from a low of $0.6403 (Jul 18, 2018) to a high of $1.4470 (Apr 14, 2021), with a median of $0.8627 per ML.
Are there cheaper alternatives to DIPHENHYDRAMINE 50 MG/ML VIAL?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DIPHENHYDRAMINE 500 MG/10 ML VL, is $0.7900 per ML — about 15% below DIPHENHYDRAMINE 50 MG/ML VIAL.
Who manufactures DIPHENHYDRAMINE 50 MG/ML VIAL?
DIPHENHYDRAMINE 50 MG/ML VIAL (NDC 00641037625) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.