Product Information

ROFLUMILAST 250 MCG TABLET is a generic product labeled by Ascend Laboratories, LLC, priced at $1.9969 per EA under NDC 67877073093. Its NADAC has been published 59 times since Jul 9, 2025.

FDA first approved this application on Apr 18, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ROFLUMILAST 250 MCG TABLET

Roflumilast
$1.9969per EA

Strength

250 ug/1

NDC

67877073093

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ROFLUMILAST

Approval Type

Generic (ANDA)

FDA Application

ANDA212490

FDA Approved

4/18/2023

TE Code

AB

On Market Since

3/14/2025

Pharmacological Classes

Phosphodiesterase 4 Inhibitor
Phosphodiesterase 4 Inhibitors

Price Statistics

The NADAC for ROFLUMILAST 250 MCG TABLET has been published 59 times since Jul 9, 2025, and over the history we have for it it has declined 12.1%. The table below summarizes its recorded NADAC range and movement.

Current price$1.9969 per EA
All-time high$2.4855 (Sep 10, 2025)
All-time low$1.9069 (Jun 17, 2026)
52-week high$2.4855
52-week low$1.9069
Median price$2.2824
Average price$2.1927
Largest weekly change-8.5% (Apr 22, 2026)
Weeks tracked59
Tracking sinceJul 9, 2025

Price History

1W

+1.9%

1M

+1.9%

3M

+2.5%

6M

-8.9%

1Y

-19.7%

3Y

N/A

5Y

N/A

All

-12.1%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ROFLUMILAST 250 MCG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ROFLUMILAST 250 MCG TABLET, manufactured by Ascend Laboratories, LLC, is $1.9969 per EA (NDC 67877073093), effective Aug 19, 2026.

How has the price of ROFLUMILAST 250 MCG TABLET changed over time?

Over the history we have for it, the NADAC for ROFLUMILAST 250 MCG TABLET has declined 12.1%. It has been tracked across 59 weekly CMS publications since Jul 9, 2025.

What are the highest and lowest recorded NADAC prices for ROFLUMILAST 250 MCG TABLET?

Since Jul 9, 2025, the NADAC for ROFLUMILAST 250 MCG TABLET has ranged from a low of $1.9069 (Jun 17, 2026) to a high of $2.4855 (Sep 10, 2025), with a median of $2.2824 per EA.

Are there cheaper alternatives to ROFLUMILAST 250 MCG TABLET?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ROFLUMILAST 250 MCG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures ROFLUMILAST 250 MCG TABLET?

ROFLUMILAST 250 MCG TABLET (NDC 67877073093) is labeled by Ascend Laboratories, LLC, and CMS classifies it as a generic product.