Product Information

BUPROPION HCL XL 300 MG TABLET is a generic product labeled by BluePoint Laboratories, priced at $0.1115 per EA under NDC 68001052005. Its NADAC has been published 212 times since Jun 8, 2022.

BUPROPION HCL XL 300 MG TABLET

BUPROPION HYDROCHLORIDE
$0.1115per EA

Strength

300 mg/1

NDC

68001052005

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA210497

On Market Since

12/13/2021

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 212 times since Jun 8, 2022, and over the history we have for it it has declined 37.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1115 per EA
All-time high$0.1988 (Feb 14, 2024)
All-time low$0.1033 (Feb 18, 2026)
52-week high$0.1504
52-week low$0.1033
Median price$0.1517
Average price$0.1517
Largest weekly change-27.4% (Feb 21, 2024)
Weeks tracked212
Tracking sinceJun 8, 2022

Price History

1W

0.0%

1M

-3.4%

3M

+3.9%

6M

-11.5%

1Y

-25.9%

3Y

-35.5%

5Y

N/A

All

-37.2%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by BluePoint Laboratories, is $0.1115 per EA (NDC 68001052005), effective Jun 24, 2026.

How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 37.2%. It has been tracked across 212 weekly CMS publications since Jun 8, 2022.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?

Since Jun 8, 2022, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1033 (Feb 18, 2026) to a high of $0.1988 (Feb 14, 2024), with a median of $0.1517 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?

Yes. 2 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, BUPROPION HCL XL 300 MG TABLET, is $0.1073 per EA — about 4% below BUPROPION HCL XL 300 MG TABLET.

Who manufactures BUPROPION HCL XL 300 MG TABLET?

BUPROPION HCL XL 300 MG TABLET (NDC 68001052005) is labeled by BluePoint Laboratories, and CMS classifies it as a generic product.