Product Information

LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.0750 per EA under NDC 68180021606. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on May 21, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB

Losartan Potassium and Hydrochlorothiazide
$0.0750per EA

Strength

12.5; 100 mg/1; mg/1

NDC

68180021606

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA078245

FDA Approved

5/21/2010

TE Code

AB

On Market Since

10/6/2010

Pharmacological Classes

Angiotensin 2 Receptor Antagonists
Angiotensin 2 Receptor Blocker
Increased Diuresis
Thiazide Diuretic
Thiazides

Price Statistics

The NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 40.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0750 per EA
All-time high$0.2088 (Apr 13, 2022)
All-time low$0.0742 (Jul 22, 2026)
52-week high$0.0973
52-week low$0.0742
Median price$0.1190
Average price$0.1207
Largest weekly change+42.6% (Dec 18, 2019)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+1.1%

1M

+1.1%

3M

-0.6%

6M

-3.5%

1Y

-23.0%

3Y

-40.4%

5Y

-53.1%

All

-40.9%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB, manufactured by Lupin Pharmaceuticals Inc., is $0.0750 per EA (NDC 68180021606), effective Aug 19, 2026.

How has the price of LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB changed over time?

Over the history we have for it, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB has declined 40.9%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?

Since Nov 28, 2013, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB has ranged from a low of $0.0742 (Jul 22, 2026) to a high of $0.2088 (Apr 13, 2022), with a median of $0.1190 per EA.

Are there cheaper alternatives to LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?

5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB in a comparable dosage form, but none are currently priced below it.

Who manufactures LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?

LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB (NDC 68180021606) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.