Product Information
CLOBETASOL 0.05% TOPICAL LOTN is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.3381 per ML under NDC 68180053601. Its NADAC has been published 444 times since Feb 21, 2018.
FDA first approved this application on Sep 22, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.05 g/100mL
Manufacturer
Lupin Pharmaceuticals Inc.NDC
68180053601
Classification
Generic
Dosage Form
LOTION
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA209147FDA Approved
9/22/2017
TE Code
AB
On Market Since
1/30/2018
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% TOPICAL LOTN has been published 444 times since Feb 21, 2018, and over the history we have for it it has declined 84.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3381 per ML |
|---|---|
| All-time high | $2.6588 (Jul 11, 2018) |
| All-time low | $0.1980 (Jul 17, 2024) |
| 52-week high | $0.3903 |
| 52-week low | $0.3197 |
| Median price | $0.8145 |
| Average price | $0.8657 |
| Largest weekly change | +66.7% (Oct 20, 2021) |
| Weeks tracked | 444 |
| Tracking since | Feb 21, 2018 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 17% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% TOPICAL LOTN?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% TOPICAL LOTN, manufactured by Lupin Pharmaceuticals Inc., is $0.3381 per ML (NDC 68180053601), effective Aug 19, 2026.
How has the price of CLOBETASOL 0.05% TOPICAL LOTN changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% TOPICAL LOTN has declined 84.7%. It has been tracked across 444 weekly CMS publications since Feb 21, 2018.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% TOPICAL LOTN?
Since Feb 21, 2018, the NADAC for CLOBETASOL 0.05% TOPICAL LOTN has ranged from a low of $0.1980 (Jul 17, 2024) to a high of $2.6588 (Jul 11, 2018), with a median of $0.8145 per ML.
Are there cheaper alternatives to CLOBETASOL 0.05% TOPICAL LOTN?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% TOPICAL LOTN, is $0.2813 per ML — about 17% below CLOBETASOL 0.05% TOPICAL LOTN.
Who manufactures CLOBETASOL 0.05% TOPICAL LOTN?
CLOBETASOL 0.05% TOPICAL LOTN (NDC 68180053601) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.