Product Information

CLOBETASOL 0.05% CREAM is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.1681 per GM under NDC 68180095602. Its NADAC has been published 411 times since Oct 10, 2018.

FDA first approved this application on Jan 30, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CLOBETASOL 0.05% CREAM

Clobetasol Propionate
$0.1681per GM

Strength

.5 mg/g

NDC

68180095602

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

CLOBETASOL PROPIONATE

Approval Type

Generic (ANDA)

FDA Application

ANDA210208

FDA Approved

1/30/2018

TE Code

AB1

On Market Since

8/17/2018

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for CLOBETASOL 0.05% CREAM has been published 411 times since Oct 10, 2018, and over the history we have for it it has declined 85.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1681 per GM
All-time high$1.1705 (Oct 10, 2018)
All-time low$0.1128 (Nov 20, 2024)
52-week high$0.1873
52-week low$0.1681
Median price$0.2691
Average price$0.4419
Largest weekly change+41.2% (Aug 21, 2024)
Weeks tracked411
Tracking sinceOct 10, 2018

Price History

1W

-2.2%

1M

-2.2%

3M

-5.5%

6M

-3.3%

1Y

-10.2%

3Y

-24.4%

5Y

-76.2%

All

-85.6%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 31% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CLOBETASOL 0.05% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by Lupin Pharmaceuticals Inc., is $0.1681 per GM (NDC 68180095602), effective Aug 19, 2026.

How has the price of CLOBETASOL 0.05% CREAM changed over time?

Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has declined 85.6%. It has been tracked across 411 weekly CMS publications since Oct 10, 2018.

What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?

Since Oct 10, 2018, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.1128 (Nov 20, 2024) to a high of $1.1705 (Oct 10, 2018), with a median of $0.2691 per GM.

Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% CREAM, is $0.1152 per GM — about 31% below CLOBETASOL 0.05% CREAM.

Who manufactures CLOBETASOL 0.05% CREAM?

CLOBETASOL 0.05% CREAM (NDC 68180095602) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.