Product Information
CLOBETASOL 0.05% CREAM is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.1427 per GM under NDC 68180095604. Its NADAC has been published 411 times since Oct 10, 2018.
FDA first approved this application on Jan 30, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Lupin Pharmaceuticals Inc.NDC
68180095604
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA210208FDA Approved
1/30/2018
TE Code
AB1
On Market Since
8/17/2018
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% CREAM has been published 411 times since Oct 10, 2018, and over the history we have for it it has declined 85.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1427 per GM |
|---|---|
| All-time high | $0.9572 (Oct 10, 2018) |
| All-time low | $0.1063 (Feb 18, 2026) |
| 52-week high | $0.1504 |
| 52-week low | $0.1063 |
| Median price | $0.2925 |
| Average price | $0.4033 |
| Largest weekly change | +48.5% (Feb 22, 2023) |
| Weeks tracked | 411 |
| Tracking since | Oct 10, 2018 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 19% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by Lupin Pharmaceuticals Inc., is $0.1427 per GM (NDC 68180095604), effective Aug 19, 2026.
How has the price of CLOBETASOL 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has declined 85.1%. It has been tracked across 411 weekly CMS publications since Oct 10, 2018.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?
Since Oct 10, 2018, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.1063 (Feb 18, 2026) to a high of $0.9572 (Oct 10, 2018), with a median of $0.2925 per GM.
Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% CREAM, is $0.1152 per GM — about 19% below CLOBETASOL 0.05% CREAM.
Who manufactures CLOBETASOL 0.05% CREAM?
CLOBETASOL 0.05% CREAM (NDC 68180095604) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.