Product Information
TOPIRAMATE 25 MG SPRINKLE CAP is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.2547 per EA under NDC 68382000514. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Oct 14, 2009. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382000514
Classification
Generic
Dosage Form
CAPSULE, COATED PELLETS
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
TOPIRAMATEApproval Type
Generic (ANDA)
FDA Application
ANDA078877FDA Approved
10/14/2009
TE Code
AB
On Market Since
10/14/2009
Pharmacological Classes
Price Statistics
The NADAC for TOPIRAMATE 25 MG SPRINKLE CAP has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 49.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2547 per EA |
|---|---|
| All-time high | $0.8567 (Dec 16, 2020) |
| All-time low | $0.2547 (Aug 19, 2026) |
| 52-week high | $0.4019 |
| 52-week low | $0.2547 |
| Median price | $0.4809 |
| Average price | $0.5341 |
| Largest weekly change | +77.5% (Jan 22, 2020) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TOPIRAMATE 25 MG SPRINKLE CAP?
The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE 25 MG SPRINKLE CAP, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.2547 per EA (NDC 68382000514), effective Aug 19, 2026.
How has the price of TOPIRAMATE 25 MG SPRINKLE CAP changed over time?
Over the history we have for it, the NADAC for TOPIRAMATE 25 MG SPRINKLE CAP has declined 49.9%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for TOPIRAMATE 25 MG SPRINKLE CAP?
Since Nov 28, 2013, the NADAC for TOPIRAMATE 25 MG SPRINKLE CAP has ranged from a low of $0.2547 (Aug 19, 2026) to a high of $0.8567 (Dec 16, 2020), with a median of $0.4809 per EA.
Are there cheaper alternatives to TOPIRAMATE 25 MG SPRINKLE CAP?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TOPIRAMATE 25 MG SPRINKLE CAP in a comparable dosage form, but none are currently priced below it.
Who manufactures TOPIRAMATE 25 MG SPRINKLE CAP?
TOPIRAMATE 25 MG SPRINKLE CAP (NDC 68382000514) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.