Product Information

OMEPRAZOLE DR 40 MG CAPSULE is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.0494 per EA under NDC 68382050005. Its NADAC has been published 43 times since Oct 29, 2025.

FDA first approved this application on Nov 19, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

OMEPRAZOLE DR 40 MG CAPSULE

Omeprazole
$0.0494per EA

Strength

40 mg/1

NDC

68382050005

Classification

Generic

Dosage Form

CAPSULE, DELAYED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

OMEPRAZOLE

Approval Type

Generic (ANDA)

FDA Application

ANDA091352

FDA Approved

11/19/2012

TE Code

AB

On Market Since

11/23/2012

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Proton Pump Inhibitor
Proton Pump Inhibitors

Price Statistics

The NADAC for OMEPRAZOLE DR 40 MG CAPSULE has been published 43 times since Oct 29, 2025, and over the history we have for it it has declined 4.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0494 per EA
All-time high$0.0520 (Jan 14, 2026)
All-time low$0.0494 (Aug 19, 2026)
52-week high$0.0520
52-week low$0.0494
Median price$0.0507
Average price$0.0509
Largest weekly change-1.5% (Feb 18, 2026)
Weeks tracked43
Tracking sinceOct 29, 2025

Price History

1W

-1.5%

1M

-1.5%

3M

-2.5%

6M

-2.7%

1Y

N/A

3Y

N/A

5Y

N/A

All

-4.1%

Generic Alternatives

The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of OMEPRAZOLE DR 40 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for OMEPRAZOLE DR 40 MG CAPSULE, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.0494 per EA (NDC 68382050005), effective Aug 19, 2026.

How has the price of OMEPRAZOLE DR 40 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for OMEPRAZOLE DR 40 MG CAPSULE has declined 4.1%. It has been tracked across 43 weekly CMS publications since Oct 29, 2025.

What are the highest and lowest recorded NADAC prices for OMEPRAZOLE DR 40 MG CAPSULE?

Since Oct 29, 2025, the NADAC for OMEPRAZOLE DR 40 MG CAPSULE has ranged from a low of $0.0494 (Aug 19, 2026) to a high of $0.0520 (Jan 14, 2026), with a median of $0.0507 per EA.

Are there cheaper alternatives to OMEPRAZOLE DR 40 MG CAPSULE?

11 manufacturers publish a NADAC-priced product with the same active ingredient and strength as OMEPRAZOLE DR 40 MG CAPSULE in a comparable dosage form, but none are currently priced below it.

Who manufactures OMEPRAZOLE DR 40 MG CAPSULE?

OMEPRAZOLE DR 40 MG CAPSULE (NDC 68382050005) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.