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Historical record - last NADAC effective date: 8/22/2018

Product Information

GLYBURIDE-METFORMIN 2.5-500 MG is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.0533 per EA under NDC 68382065405. Its NADAC has been published 103 times since Sep 21, 2016.

FDA first approved this application on Feb 29, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

GLYBURIDE-METFORMIN 2.5-500 MG

glyburide and metformin hydrochloride
$0.0533per EA

Strength

2.5; 500 mg/1; mg/1

NDC

68382065405

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/22/2018

Approval Type

Generic (ANDA)

FDA Application

ANDA206748

FDA Approved

2/29/2016

TE Code

AB

On Market Since

4/7/2016

Pharmacological Classes

Biguanide
Biguanides
Sulfonylurea Compounds
Sulfonylurea

Price Statistics

The NADAC for GLYBURIDE-METFORMIN 2.5-500 MG has been published 103 times since Sep 21, 2016, and over the history we have for it it has declined 25.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0533 per EA
All-time high$0.0806 (Nov 16, 2016)
All-time low$0.0496 (Apr 18, 2018)
Median price$0.0625
Average price$0.0624
Largest weekly change+26.8% (May 23, 2018)
Weeks tracked103
Tracking sinceSep 21, 2016

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

N/A

5Y

N/A

All

-25.2%

Last surveyed Sep 5, 2018 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

GLYBURIDE-METFORMIN 2.5-500 MG
Generic
68382065401•Zydus Pharmaceuticals (USA) Inc.
$0.0533

Related Drugs

Same classification

METFORMIN HCL 500 MG TABLET
Generic
71093013204•ACI Healthcare USA, Inc.
$0.0140
per EA
METFORMIN HCL 500 MG TABLET
Generic
71093013205•ACI Healthcare USA, Inc.
$0.0140
per EA
METFORMIN HCL 500 MG TABLET
Generic
71093013206•ACI Healthcare USA, Inc.
$0.0140
per EA
METFORMIN HCL 500 MG TABLET
Generic
00378718505•Mylan Pharmaceuticals Inc.
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
00904716261•Major Pharmaceuticals
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
23155084101•Heritage Pharmaceuticals Inc.
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
23155084105•Heritage Pharmaceuticals Inc.
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
23155084110•Heritage Pharmaceuticals Inc.
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
42385094701•Laurus Labs Limited
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
42385094705•Laurus Labs Limited
$0.0142
per EA

Frequently asked questions

What is the NADAC price of GLYBURIDE-METFORMIN 2.5-500 MG?

The current National Average Drug Acquisition Cost (NADAC) for GLYBURIDE-METFORMIN 2.5-500 MG, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.0533 per EA (NDC 68382065405), effective Sep 5, 2018.

How has the price of GLYBURIDE-METFORMIN 2.5-500 MG changed over time?

Over the history we have for it, the NADAC for GLYBURIDE-METFORMIN 2.5-500 MG has declined 25.2%. It has been tracked across 103 weekly CMS publications since Sep 21, 2016.

What are the highest and lowest recorded NADAC prices for GLYBURIDE-METFORMIN 2.5-500 MG?

Since Sep 21, 2016, the NADAC for GLYBURIDE-METFORMIN 2.5-500 MG has ranged from a low of $0.0496 (Apr 18, 2018) to a high of $0.0806 (Nov 16, 2016), with a median of $0.0625 per EA.

Are there cheaper alternatives to GLYBURIDE-METFORMIN 2.5-500 MG?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as GLYBURIDE-METFORMIN 2.5-500 MG in a comparable dosage form, but none are currently priced below it.

Who manufactures GLYBURIDE-METFORMIN 2.5-500 MG?

GLYBURIDE-METFORMIN 2.5-500 MG (NDC 68382065405) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.