Product Information
METHYLPREDNISOLONE 16 MG TAB is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $1.4461 per EA under NDC 68382091818. Its NADAC has been published 392 times since Oct 3, 2018.
FDA first approved this application on Apr 23, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
16 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382091818
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
METHYLPREDNISOLONEApproval Type
Generic (ANDA)
FDA Application
ANDA206751FDA Approved
4/23/2018
TE Code
AB
On Market Since
5/1/2018
Pharmacological Classes
Price Statistics
The NADAC for METHYLPREDNISOLONE 16 MG TAB has been published 392 times since Oct 3, 2018, and over the history we have for it it has declined 29.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.4461 per EA |
|---|---|
| All-time high | $2.0539 (Jun 12, 2019) |
| All-time low | $1.0554 (May 17, 2023) |
| 52-week high | $1.6239 |
| 52-week low | $1.3724 |
| Median price | $1.6239 |
| Average price | $1.6491 |
| Largest weekly change | +51.1% (Jul 19, 2023) |
| Weeks tracked | 392 |
| Tracking since | Oct 3, 2018 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Zydus Pharmaceuticals (USA) Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
methylprednisolone market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Corticosteroid class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METHYLPREDNISOLONE 16 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for METHYLPREDNISOLONE 16 MG TAB, manufactured by Zydus Pharmaceuticals (USA) Inc., is $1.4461 per EA (NDC 68382091818), effective Sep 30, 2026.
How has the price of METHYLPREDNISOLONE 16 MG TAB changed over time?
Over the history we have for it, the NADAC for METHYLPREDNISOLONE 16 MG TAB has declined 29.6%. It has been tracked across 392 weekly CMS publications since Oct 3, 2018.
What are the highest and lowest recorded NADAC prices for METHYLPREDNISOLONE 16 MG TAB?
Since Oct 3, 2018, the NADAC for METHYLPREDNISOLONE 16 MG TAB has ranged from a low of $1.0554 (May 17, 2023) to a high of $2.0539 (Jun 12, 2019), with a median of $1.6239 per EA.
Are there cheaper alternatives to METHYLPREDNISOLONE 16 MG TAB?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as METHYLPREDNISOLONE 16 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures METHYLPREDNISOLONE 16 MG TAB?
METHYLPREDNISOLONE 16 MG TAB (NDC 68382091818) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.