Product Information

SERTRALINE HCL 25 MG TABLET is a generic product labeled by Legacy Pharmaceutical Packaging, LLC, priced at $0.0286 per EA under NDC 68645052154. Its NADAC has been published 505 times since Oct 26, 2016.

SERTRALINE HCL 25 MG TABLET

Sertraline Hydrochloride
$0.0286per EA

Strength

25 mg/1

NDC

68645052154

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

SERTRALINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA077397

On Market Since

7/21/2016

Pharmacological Classes

Cytochrome P450 2D6 Inhibitors
Serotonin Reuptake Inhibitor
Serotonin Uptake Inhibitors

Price Statistics

The NADAC for SERTRALINE HCL 25 MG TABLET has been published 505 times since Oct 26, 2016, and over the history we have for it it has declined 50.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0286 per EA
All-time high$0.0786 (Sep 16, 2020)
All-time low$0.0285 (Nov 20, 2024)
52-week high$0.0336
52-week low$0.0286
Median price$0.0554
Average price$0.0513
Largest weekly change+31.1% (Jul 22, 2020)
Weeks tracked505
Tracking sinceOct 26, 2016

Price History

1W

0.0%

1M

-3.8%

3M

-9.9%

6M

-13.0%

1Y

-11.3%

3Y

-31.4%

5Y

-62.1%

All

-50.1%

Generic Alternatives

The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SERTRALINE HCL 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SERTRALINE HCL 25 MG TABLET, manufactured by Legacy Pharmaceutical Packaging, LLC, is $0.0286 per EA (NDC 68645052154), effective Jun 24, 2026.

How has the price of SERTRALINE HCL 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for SERTRALINE HCL 25 MG TABLET has declined 50.1%. It has been tracked across 505 weekly CMS publications since Oct 26, 2016.

What are the highest and lowest recorded NADAC prices for SERTRALINE HCL 25 MG TABLET?

Since Oct 26, 2016, the NADAC for SERTRALINE HCL 25 MG TABLET has ranged from a low of $0.0285 (Nov 20, 2024) to a high of $0.0786 (Sep 16, 2020), with a median of $0.0554 per EA.

Are there cheaper alternatives to SERTRALINE HCL 25 MG TABLET?

6 NADAC-published products share the same active ingredient, strength, and dosage form as SERTRALINE HCL 25 MG TABLET, but none are currently priced below it.

Who manufactures SERTRALINE HCL 25 MG TABLET?

SERTRALINE HCL 25 MG TABLET (NDC 68645052154) is labeled by Legacy Pharmaceutical Packaging, LLC, and CMS classifies it as a generic product.