Product Information

SERTRALINE HCL 25 MG TABLET is a generic product labeled by Cipla USA Inc., priced at $0.0282 per EA under NDC 69097083312. Its NADAC has been published 519 times since Sep 14, 2016.

FDA first approved this application on Feb 6, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

SERTRALINE HCL 25 MG TABLET

Sertraline Hydrochloride
$0.0282per EA

Strength

25 mg/1

Manufacturer

Cipla USA Inc.

NDC

69097083312

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SERTRALINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA077397

FDA Approved

2/6/2007

TE Code

AB

On Market Since

7/21/2016

Pharmacological Classes

Cytochrome P450 2D6 Inhibitors
Serotonin Reuptake Inhibitor
Serotonin Uptake Inhibitors

Price Statistics

The NADAC for SERTRALINE HCL 25 MG TABLET has been published 519 times since Sep 14, 2016, and over the history we have for it it has declined 55.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0282 per EA
All-time high$0.0786 (Sep 16, 2020)
All-time low$0.0282 (Aug 19, 2026)
52-week high$0.0336
52-week low$0.0282
Median price$0.0546
Average price$0.0510
Largest weekly change+31.1% (Jul 22, 2020)
Weeks tracked519
Tracking sinceSep 14, 2016

Price History

1W

-1.3%

1M

-1.3%

3M

-5.4%

6M

-11.9%

1Y

-14.8%

3Y

-24.9%

5Y

-58.8%

All

-55.2%

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SERTRALINE HCL 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SERTRALINE HCL 25 MG TABLET, manufactured by Cipla USA Inc., is $0.0282 per EA (NDC 69097083312), effective Aug 19, 2026.

How has the price of SERTRALINE HCL 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for SERTRALINE HCL 25 MG TABLET has declined 55.2%. It has been tracked across 519 weekly CMS publications since Sep 14, 2016.

What are the highest and lowest recorded NADAC prices for SERTRALINE HCL 25 MG TABLET?

Since Sep 14, 2016, the NADAC for SERTRALINE HCL 25 MG TABLET has ranged from a low of $0.0282 (Aug 19, 2026) to a high of $0.0786 (Sep 16, 2020), with a median of $0.0546 per EA.

Are there cheaper alternatives to SERTRALINE HCL 25 MG TABLET?

7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SERTRALINE HCL 25 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures SERTRALINE HCL 25 MG TABLET?

SERTRALINE HCL 25 MG TABLET (NDC 69097083312) is labeled by Cipla USA Inc., and CMS classifies it as a generic product.