Product Information

BUPROPION HCL XL 300 MG TABLET is a generic product labeled by Cipla USA Inc., priced at $0.1014 per EA under NDC 69097087602. Its NADAC has been published 509 times since Nov 23, 2016.

FDA first approved this application on Aug 26, 2016.

BUPROPION HCL XL 300 MG TABLET

bupropion hydrochloride
$0.1014per EA

Strength

300 mg/1

Manufacturer

Cipla USA Inc.

NDC

69097087602

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA206556

FDA Approved

8/26/2016

On Market Since

8/29/2016

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 509 times since Nov 23, 2016, and over the history we have for it it has declined 80.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1014 per EA
All-time high$0.5632 (Jan 11, 2017)
All-time low$0.1014 (Aug 19, 2026)
52-week high$0.1492
52-week low$0.1014
Median price$0.1988
Average price$0.2582
Largest weekly change-33.9% (Sep 18, 2019)
Weeks tracked509
Tracking sinceNov 23, 2016

Price History

1W

-2.6%

1M

-9.1%

3M

-12.2%

6M

-1.9%

1Y

-31.6%

3Y

-43.1%

5Y

-50.9%

All

-80.1%

Generic Alternatives

The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by Cipla USA Inc., is $0.1014 per EA (NDC 69097087602), effective Aug 19, 2026.

How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 80.1%. It has been tracked across 509 weekly CMS publications since Nov 23, 2016.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?

Since Nov 23, 2016, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1014 (Aug 19, 2026) to a high of $0.5632 (Jan 11, 2017), with a median of $0.1988 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?

9 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL XL 300 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPROPION HCL XL 300 MG TABLET?

BUPROPION HCL XL 300 MG TABLET (NDC 69097087602) is labeled by Cipla USA Inc., and CMS classifies it as a generic product.