Historical record - last NADAC effective date: 4/20/2022
Product Information
LOPREEZA 1 MG-0.5 MG TABLET is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $1.0848 per EA under NDC 69238161006. Its NADAC has been published 151 times since Jun 12, 2019.
FDA first approved this application on Nov 18, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1; .5 mg/1; mg/1
Manufacturer
Amneal Pharmaceuticals NY LLCNDC
69238161006
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
4/20/2022
Active Ingredients
ESTRADIOL; NORETHINDRONE ACETATEApproval Type
New Drug (NDA)
FDA Application
NDA020907FDA Approved
11/18/1998
TE Code
AB
On Market Since
1/7/2019
Price Statistics
The NADAC for LOPREEZA 1 MG-0.5 MG TABLET has been published 151 times since Jun 12, 2019, and over the history we have for it it has declined 51.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0848 per EA |
|---|---|
| All-time high | $2.2493 (Jul 10, 2019) |
| All-time low | $1.0395 (Dec 22, 2021) |
| Median price | $1.9750 |
| Average price | $1.8173 |
| Largest weekly change | -24.3% (Aug 18, 2021) |
| Weeks tracked | 151 |
| Tracking since | Jun 12, 2019 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
N/A
5Y
-25.1%
All
-51.1%
Last surveyed Apr 27, 2022 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
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Same classification
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Manufacturer
Amneal Pharmaceuticals NY LLC manufacturer profile
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Drug market
estradiol/norethindrone acetate market comparison
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Therapeutic class
Estrogen class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LOPREEZA 1 MG-0.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for LOPREEZA 1 MG-0.5 MG TABLET, manufactured by Amneal Pharmaceuticals NY LLC, is $1.0848 per EA (NDC 69238161006), effective Apr 27, 2022.
How has the price of LOPREEZA 1 MG-0.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for LOPREEZA 1 MG-0.5 MG TABLET has declined 51.1%. It has been tracked across 151 weekly CMS publications since Jun 12, 2019.
What are the highest and lowest recorded NADAC prices for LOPREEZA 1 MG-0.5 MG TABLET?
Since Jun 12, 2019, the NADAC for LOPREEZA 1 MG-0.5 MG TABLET has ranged from a low of $1.0395 (Dec 22, 2021) to a high of $2.2493 (Jul 10, 2019), with a median of $1.9750 per EA.
Are there cheaper alternatives to LOPREEZA 1 MG-0.5 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LOPREEZA 1 MG-0.5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures LOPREEZA 1 MG-0.5 MG TABLET?
LOPREEZA 1 MG-0.5 MG TABLET (NDC 69238161006) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.