Historical record - last NADAC effective date: 4/20/2022

Product Information

LOPREEZA 1 MG-0.5 MG TABLET is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $1.0848 per EA under NDC 69238161006. Its NADAC has been published 151 times since Jun 12, 2019.

FDA first approved this application on Nov 18, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LOPREEZA 1 MG-0.5 MG TABLET

estradiol/norethindrone acetate
$1.0848per EA

Strength

1; .5 mg/1; mg/1

NDC

69238161006

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

4/20/2022

Approval Type

New Drug (NDA)

FDA Application

NDA020907

FDA Approved

11/18/1998

TE Code

AB

On Market Since

1/7/2019

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen
Progesterone Congeners
Progestin

Price Statistics

The NADAC for LOPREEZA 1 MG-0.5 MG TABLET has been published 151 times since Jun 12, 2019, and over the history we have for it it has declined 51.1%. The table below summarizes its recorded NADAC range and movement.

Current price$1.0848 per EA
All-time high$2.2493 (Jul 10, 2019)
All-time low$1.0395 (Dec 22, 2021)
Median price$1.9750
Average price$1.8173
Largest weekly change-24.3% (Aug 18, 2021)
Weeks tracked151
Tracking sinceJun 12, 2019

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

N/A

5Y

-9.0%

All

-51.1%

Last surveyed Apr 27, 2022 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LOPREEZA 1 MG-0.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for LOPREEZA 1 MG-0.5 MG TABLET, manufactured by Amneal Pharmaceuticals NY LLC, is $1.0848 per EA (NDC 69238161006), effective Apr 27, 2022.

How has the price of LOPREEZA 1 MG-0.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for LOPREEZA 1 MG-0.5 MG TABLET has declined 51.1%. It has been tracked across 151 weekly CMS publications since Jun 12, 2019.

What are the highest and lowest recorded NADAC prices for LOPREEZA 1 MG-0.5 MG TABLET?

Since Jun 12, 2019, the NADAC for LOPREEZA 1 MG-0.5 MG TABLET has ranged from a low of $1.0395 (Dec 22, 2021) to a high of $2.2493 (Jul 10, 2019), with a median of $1.9750 per EA.

Are there cheaper alternatives to LOPREEZA 1 MG-0.5 MG TABLET?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LOPREEZA 1 MG-0.5 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures LOPREEZA 1 MG-0.5 MG TABLET?

LOPREEZA 1 MG-0.5 MG TABLET (NDC 69238161006) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.