Product Information
ESTRADIOL 0.5 MG TABLET is a generic product labeled by Teva Pharmaceuticals USA Inc., priced at $0.0617 per EA under NDC 00555089902. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Oct 22, 1997. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/1
Manufacturer
Teva Pharmaceuticals USA Inc.NDC
00555089902
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA040197FDA Approved
10/22/1997
TE Code
AB
On Market Since
10/28/1997
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.5 MG TABLET has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 9.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0617 per EA |
|---|---|
| All-time high | $0.1226 (Aug 16, 2017) |
| All-time low | $0.0563 (Nov 20, 2024) |
| 52-week high | $0.0700 |
| 52-week low | $0.0583 |
| Median price | $0.0906 |
| Average price | $0.0890 |
| Largest weekly change | +86.5% (Jul 22, 2015) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Teva Pharmaceuticals USA Inc. manufacturer profile
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Drug market
Estradiol market comparison
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Therapeutic class
Estrogen class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.5 MG TABLET, manufactured by Teva Pharmaceuticals USA Inc., is $0.0617 per EA (NDC 00555089902), effective Sep 30, 2026.
How has the price of ESTRADIOL 0.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.5 MG TABLET has declined 9.5%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.5 MG TABLET?
Since Nov 28, 2013, the NADAC for ESTRADIOL 0.5 MG TABLET has ranged from a low of $0.0563 (Nov 20, 2024) to a high of $0.1226 (Aug 16, 2017), with a median of $0.0906 per EA.
Are there cheaper alternatives to ESTRADIOL 0.5 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ESTRADIOL 0.5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures ESTRADIOL 0.5 MG TABLET?
ESTRADIOL 0.5 MG TABLET (NDC 00555089902) is labeled by Teva Pharmaceuticals USA Inc., and CMS classifies it as a generic product.