Product Information

ESTRADIOL 0.5 MG TABLET is a generic product labeled by Teva Pharmaceuticals USA Inc., priced at $0.0608 per EA under NDC 00555089902. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Oct 22, 1997. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ESTRADIOL 0.5 MG TABLET

Estradiol
$0.0608per EA

Strength

.5 mg/1

NDC

00555089902

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ESTRADIOL

Approval Type

Generic (ANDA)

FDA Application

ANDA040197

FDA Approved

10/22/1997

TE Code

AB

On Market Since

10/28/1997

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for ESTRADIOL 0.5 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 10.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0608 per EA
All-time high$0.1226 (Aug 16, 2017)
All-time low$0.0563 (Nov 20, 2024)
52-week high$0.0705
52-week low$0.0583
Median price$0.0906
Average price$0.0893
Largest weekly change+86.5% (Jul 22, 2015)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+1.8%

1M

+1.8%

3M

+4.2%

6M

+0.6%

1Y

-13.7%

3Y

-16.1%

5Y

-39.3%

All

-10.8%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ESTRADIOL 0.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.5 MG TABLET, manufactured by Teva Pharmaceuticals USA Inc., is $0.0608 per EA (NDC 00555089902), effective Aug 19, 2026.

How has the price of ESTRADIOL 0.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for ESTRADIOL 0.5 MG TABLET has declined 10.8%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.5 MG TABLET?

Since Nov 28, 2013, the NADAC for ESTRADIOL 0.5 MG TABLET has ranged from a low of $0.0563 (Nov 20, 2024) to a high of $0.1226 (Aug 16, 2017), with a median of $0.0906 per EA.

Are there cheaper alternatives to ESTRADIOL 0.5 MG TABLET?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ESTRADIOL 0.5 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures ESTRADIOL 0.5 MG TABLET?

ESTRADIOL 0.5 MG TABLET (NDC 00555089902) is labeled by Teva Pharmaceuticals USA Inc., and CMS classifies it as a generic product.