Product Information
ESTRADIOL 0.5 MG TABLET is a generic product labeled by NorthStar Rx LLC, priced at $0.0608 per EA under NDC 72603027301. Its NADAC has been published 103 times since Sep 4, 2024.
FDA first approved this application on Sep 6, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/1
Manufacturer
NorthStar Rx LLCNDC
72603027301
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA217334FDA Approved
9/6/2023
TE Code
AB
On Market Since
7/10/2024
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.5 MG TABLET has been published 103 times since Sep 4, 2024, and over the history we have for it it has declined 19.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0608 per EA |
|---|---|
| All-time high | $0.0768 (Nov 13, 2024) |
| All-time low | $0.0563 (Nov 20, 2024) |
| 52-week high | $0.0705 |
| 52-week low | $0.0583 |
| Median price | $0.0677 |
| Average price | $0.0664 |
| Largest weekly change | -26.7% (Nov 20, 2024) |
| Weeks tracked | 103 |
| Tracking since | Sep 4, 2024 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.5 MG TABLET, manufactured by NorthStar Rx LLC, is $0.0608 per EA (NDC 72603027301), effective Aug 19, 2026.
How has the price of ESTRADIOL 0.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.5 MG TABLET has declined 19.5%. It has been tracked across 103 weekly CMS publications since Sep 4, 2024.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.5 MG TABLET?
Since Sep 4, 2024, the NADAC for ESTRADIOL 0.5 MG TABLET has ranged from a low of $0.0563 (Nov 20, 2024) to a high of $0.0768 (Nov 13, 2024), with a median of $0.0677 per EA.
Are there cheaper alternatives to ESTRADIOL 0.5 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ESTRADIOL 0.5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures ESTRADIOL 0.5 MG TABLET?
ESTRADIOL 0.5 MG TABLET (NDC 72603027301) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.