Product Information

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET is a generic product labeled by Leading Pharma, LLC, priced at $0.1386 per EA under NDC 69315091001. Its NADAC has been published 315 times since Aug 12, 2020.

FDA first approved this application on Feb 20, 2020. Its Orange Book therapeutic-equivalence code is AA.

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET

diphenoxylate hydrochloride and atropine sulfate
$0.1386per EA
DEA Schedule CV

Strength

.025; 2.5 mg/1; mg/1

NDC

69315091001

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA213413

FDA Approved

2/20/2020

TE Code

AA

On Market Since

3/15/2020

Pharmacological Classes

Anticholinergic
Antidiarrheal
Cholinergic Antagonists
Cholinergic Muscarinic Antagonist
Cholinergic Muscarinic Antagonists

Price Statistics

The NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has been published 315 times since Aug 12, 2020, and over the history we have for it it has declined 47.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1386 per EA
All-time high$0.2788 (Sep 16, 2020)
All-time low$0.1298 (Nov 20, 2024)
52-week high$0.1837
52-week low$0.1371
Median price$0.1940
Average price$0.1900
Largest weekly change+55.5% (Aug 21, 2024)
Weeks tracked315
Tracking sinceAug 12, 2020

Price History

1W

+1.1%

1M

+1.1%

3M

-0.0%

6M

-11.2%

1Y

-24.6%

3Y

-23.0%

5Y

-33.2%

All

-47.1%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET, manufactured by Leading Pharma, LLC, is $0.1386 per EA (NDC 69315091001), effective Aug 19, 2026.

How has the price of DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET changed over time?

Over the history we have for it, the NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has declined 47.1%. It has been tracked across 315 weekly CMS publications since Aug 12, 2020.

What are the highest and lowest recorded NADAC prices for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

Since Aug 12, 2020, the NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has ranged from a low of $0.1298 (Nov 20, 2024) to a high of $0.2788 (Sep 16, 2020), with a median of $0.1940 per EA.

Are there cheaper alternatives to DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET (NDC 69315091001) is labeled by Leading Pharma, LLC, and CMS classifies it as a generic product.