Product Information

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET is a generic product labeled by Leading Pharma, LLC, priced at $0.1384 per EA under NDC 69315091001. Its NADAC has been published 307 times since Aug 12, 2020.

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET

diphenoxylate hydrochloride and atropine sulfate
$0.1384per EA
DEA Schedule CV

Strength

.025; 2.5 mg/1; mg/1

NDC

69315091001

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA213413

On Market Since

3/15/2020

Pharmacological Classes

Anticholinergic
Antidiarrheal
Cholinergic Antagonists
Cholinergic Muscarinic Antagonist
Cholinergic Muscarinic Antagonists

Price Statistics

The NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has been published 307 times since Aug 12, 2020, and over the history we have for it it has declined 47.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1384 per EA
All-time high$0.2788 (Sep 16, 2020)
All-time low$0.1298 (Nov 20, 2024)
52-week high$0.1840
52-week low$0.1384
Median price$0.1946
Average price$0.1914
Largest weekly change+55.5% (Aug 21, 2024)
Weeks tracked307
Tracking sinceAug 12, 2020

Price History

1W

0.0%

1M

-0.2%

3M

-7.2%

6M

-16.6%

1Y

-23.5%

3Y

-26.9%

5Y

-31.6%

All

-47.2%

Generic Alternatives

The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET, manufactured by Leading Pharma, LLC, is $0.1384 per EA (NDC 69315091001), effective Jun 24, 2026.

How has the price of DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET changed over time?

Over the history we have for it, the NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has declined 47.2%. It has been tracked across 307 weekly CMS publications since Aug 12, 2020.

What are the highest and lowest recorded NADAC prices for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

Since Aug 12, 2020, the NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has ranged from a low of $0.1298 (Nov 20, 2024) to a high of $0.2788 (Sep 16, 2020), with a median of $0.1946 per EA.

Are there cheaper alternatives to DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

4 NADAC-published products share the same active ingredient, strength, and dosage form as DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET, but none are currently priced below it.

Who manufactures DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET (NDC 69315091001) is labeled by Leading Pharma, LLC, and CMS classifies it as a generic product.