Product Information

HEADACHE RLF 250-250-65 MG CPLT is a generic product labeled by Cardinal Health, priced at $0.0649 per EA under NDC 70000006601. Its NADAC has been published 262 times since Aug 18, 2021.

HEADACHE RLF 250-250-65 MG CPLT

Acetaminophen, Aspirin, Caffeine
$0.0649per EA
OTC

Strength

250; 250; 65 mg/1; mg/1; mg/1

Manufacturer

Cardinal Health

NDC

70000006601

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M013

On Market Since

11/6/2020

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Central Nervous System Stimulant
Central Nervous System Stimulation
Cyclooxygenase Inhibitors
Decreased Platelet Aggregation
Decreased Prostaglandin Production
Methylxanthine
Nonsteroidal Anti-inflammatory Drug
Platelet Aggregation Inhibitor
Xanthines

Price Statistics

The NADAC for HEADACHE RLF 250-250-65 MG CPLT has been published 262 times since Aug 18, 2021, and over the history we have for it it has risen 8.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0649 per EA
All-time high$0.0698 (Sep 11, 2024)
All-time low$0.0530 (Nov 17, 2021)
52-week high$0.0691
52-week low$0.0635
Median price$0.0637
Average price$0.0634
Largest weekly change+17.8% (Dec 22, 2021)
Weeks tracked262
Tracking sinceAug 18, 2021

Price History

1W

-2.6%

1M

-2.6%

3M

-3.3%

6M

+1.9%

1Y

-5.4%

3Y

+9.6%

5Y

+8.9%

All

+8.9%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of HEADACHE RLF 250-250-65 MG CPLT?

The current National Average Drug Acquisition Cost (NADAC) for HEADACHE RLF 250-250-65 MG CPLT, manufactured by Cardinal Health, is $0.0649 per EA (NDC 70000006601), effective Aug 19, 2026.

How has the price of HEADACHE RLF 250-250-65 MG CPLT changed over time?

Over the history we have for it, the NADAC for HEADACHE RLF 250-250-65 MG CPLT has risen 8.9%. It has been tracked across 262 weekly CMS publications since Aug 18, 2021.

What are the highest and lowest recorded NADAC prices for HEADACHE RLF 250-250-65 MG CPLT?

Since Aug 18, 2021, the NADAC for HEADACHE RLF 250-250-65 MG CPLT has ranged from a low of $0.0530 (Nov 17, 2021) to a high of $0.0698 (Sep 11, 2024), with a median of $0.0637 per EA.

Are there cheaper alternatives to HEADACHE RLF 250-250-65 MG CPLT?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HEADACHE RLF 250-250-65 MG CPLT in a comparable dosage form, but none are currently priced below it.

Who manufactures HEADACHE RLF 250-250-65 MG CPLT?

HEADACHE RLF 250-250-65 MG CPLT (NDC 70000006601) is labeled by Cardinal Health, and CMS classifies it as a generic product.