Product Information
HEADACHE RLF 250-250-65 MG CPLT is a generic product labeled by Cardinal Health, priced at $0.0663 per EA under NDC 70000006601. Its NADAC has been published 254 times since Aug 18, 2021.
Strength
250; 250; 65 mg/1; mg/1; mg/1
Manufacturer
Cardinal HealthNDC
70000006601
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
ACETAMINOPHEN; ASPIRIN; CAFFEINEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M013On Market Since
11/6/2020
Pharmacological Classes
Price Statistics
The NADAC for HEADACHE RLF 250-250-65 MG CPLT has been published 254 times since Aug 18, 2021, and over the history we have for it it has risen 11.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0663 per EA |
|---|---|
| All-time high | $0.0698 (Sep 11, 2024) |
| All-time low | $0.0530 (Nov 17, 2021) |
| 52-week high | $0.0691 |
| 52-week low | $0.0635 |
| Median price | $0.0637 |
| Average price | $0.0633 |
| Largest weekly change | +17.8% (Dec 22, 2021) |
| Weeks tracked | 254 |
| Tracking since | Aug 18, 2021 |
Generic Alternatives
The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of HEADACHE RLF 250-250-65 MG CPLT?
The current National Average Drug Acquisition Cost (NADAC) for HEADACHE RLF 250-250-65 MG CPLT, manufactured by Cardinal Health, is $0.0663 per EA (NDC 70000006601), effective Jun 24, 2026.
How has the price of HEADACHE RLF 250-250-65 MG CPLT changed over time?
Over the history we have for it, the NADAC for HEADACHE RLF 250-250-65 MG CPLT has risen 11.2%. It has been tracked across 254 weekly CMS publications since Aug 18, 2021.
What are the highest and lowest recorded NADAC prices for HEADACHE RLF 250-250-65 MG CPLT?
Since Aug 18, 2021, the NADAC for HEADACHE RLF 250-250-65 MG CPLT has ranged from a low of $0.0530 (Nov 17, 2021) to a high of $0.0698 (Sep 11, 2024), with a median of $0.0637 per EA.
Are there cheaper alternatives to HEADACHE RLF 250-250-65 MG CPLT?
6 NADAC-published products share the same active ingredient, strength, and dosage form as HEADACHE RLF 250-250-65 MG CPLT, but none are currently priced below it.
Who manufactures HEADACHE RLF 250-250-65 MG CPLT?
HEADACHE RLF 250-250-65 MG CPLT (NDC 70000006601) is labeled by Cardinal Health, and CMS classifies it as a generic product.
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