Product Information

BRIMONIDINE-TIMOLOL 0.2%-0.5% is a generic product labeled by Somerset Therapeutics, LLC, priced at $1.9717 per ML under NDC 70069065301. Its NADAC has been published 70 times since Jun 4, 2025.

FDA first approved this application on Sep 10, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BRIMONIDINE-TIMOLOL 0.2%-0.5%

Brimonidine Tartrate and Timolol Maleate
$1.9717per ML

Strength

2; 5 mg/mL; mg/mL

NDC

70069065301

Classification

Generic

Dosage Form

SOLUTION/ DROPS

Route

OPHTHALMIC

Effective Date

9/23/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA216114

FDA Approved

9/10/2024

TE Code

AB

On Market Since

10/10/2024

Pharmacological Classes

Adrenergic alpha-Agonists
Adrenergic beta-Antagonists
alpha-Adrenergic Agonist
beta-Adrenergic Blocker

Price Statistics

The NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has been published 70 times since Jun 4, 2025, and over the history we have for it it has declined 75.0%. The table below summarizes its recorded NADAC range and movement.

Current price$1.9717 per ML
All-time high$7.8815 (Jun 11, 2025)
All-time low$1.8390 (Aug 19, 2026)
52-week high$6.8975
52-week low$1.8390
Median price$3.5461
Average price$4.1995
Largest weekly change-35.8% (Dec 17, 2025)
Weeks tracked70
Tracking sinceJun 4, 2025

Price History

1W

0.0%

1M

+7.2%

3M

-6.2%

6M

-14.2%

1Y

-71.4%

3Y

N/A

5Y

N/A

All

-75.0%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Frequently asked questions

What is the NADAC price of BRIMONIDINE-TIMOLOL 0.2%-0.5%?

The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE-TIMOLOL 0.2%-0.5%, manufactured by Somerset Therapeutics, LLC, is $1.9717 per ML (NDC 70069065301), effective Sep 30, 2026.

How has the price of BRIMONIDINE-TIMOLOL 0.2%-0.5% changed over time?

Over the history we have for it, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has declined 75.0%. It has been tracked across 70 weekly CMS publications since Jun 4, 2025.

What are the highest and lowest recorded NADAC prices for BRIMONIDINE-TIMOLOL 0.2%-0.5%?

Since Jun 4, 2025, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has ranged from a low of $1.8390 (Aug 19, 2026) to a high of $7.8815 (Jun 11, 2025), with a median of $3.5461 per ML.

Are there cheaper alternatives to BRIMONIDINE-TIMOLOL 0.2%-0.5%?

5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BRIMONIDINE-TIMOLOL 0.2%-0.5% in a comparable dosage form, but none are currently priced below it.

Who manufactures BRIMONIDINE-TIMOLOL 0.2%-0.5%?

BRIMONIDINE-TIMOLOL 0.2%-0.5% (NDC 70069065301) is labeled by Somerset Therapeutics, LLC, and CMS classifies it as a generic product.