Product Information
CLOBETASOL 0.05% CREAM is a generic product labeled by Xiromed LLC, priced at $0.1404 per GM under NDC 70700010917. Its NADAC has been published 408 times since Dec 12, 2018.
FDA first approved this application on Jun 15, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Xiromed LLCNDC
70700010917
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA210034FDA Approved
6/15/2018
TE Code
AB1
On Market Since
6/19/2018
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% CREAM has been published 408 times since Dec 12, 2018, and over the history we have for it it has declined 82.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1404 per GM |
|---|---|
| All-time high | $0.8725 (Aug 14, 2019) |
| All-time low | $0.1063 (Feb 18, 2026) |
| 52-week high | $0.1504 |
| 52-week low | $0.1063 |
| Median price | $0.2769 |
| Average price | $0.3885 |
| Largest weekly change | +48.5% (Feb 22, 2023) |
| Weeks tracked | 408 |
| Tracking since | Dec 12, 2018 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 18% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Xiromed LLC manufacturer profile
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Drug market
Clobetasol Propionate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by Xiromed LLC, is $0.1404 per GM (NDC 70700010917), effective Sep 30, 2026.
How has the price of CLOBETASOL 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has declined 82.4%. It has been tracked across 408 weekly CMS publications since Dec 12, 2018.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?
Since Dec 12, 2018, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.1063 (Feb 18, 2026) to a high of $0.8725 (Aug 14, 2019), with a median of $0.2769 per GM.
Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% CREAM, is $0.1152 per GM — about 18% below CLOBETASOL 0.05% CREAM.
Who manufactures CLOBETASOL 0.05% CREAM?
CLOBETASOL 0.05% CREAM (NDC 70700010917) is labeled by Xiromed LLC, and CMS classifies it as a generic product.