Product Information

ESTRADIOL VALERATE 200 MG/5 ML is a generic product labeled by Xiromed LLC, priced at $36.8279 per ML under NDC 70700027522. Its NADAC has been published 169 times since Jul 12, 2023.

FDA first approved this application on Apr 28, 2023. Its Orange Book therapeutic-equivalence code is AO.

ESTRADIOL VALERATE 200 MG/5 ML

Estradiol valerate
$36.8279per ML

Strength

40 mg/mL

Manufacturer

Xiromed LLC

NDC

70700027522

Classification

Generic

Dosage Form

INJECTION

Route

INTRAMUSCULAR

Effective Date

9/23/2026

Active Ingredients

ESTRADIOL VALERATE

Approval Type

Generic (ANDA)

FDA Application

ANDA216656

FDA Approved

4/28/2023

TE Code

AO

On Market Since

5/1/2023

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for ESTRADIOL VALERATE 200 MG/5 ML has been published 169 times since Jul 12, 2023, and over the history we have for it it has risen 9.2%. The table below summarizes its recorded NADAC range and movement.

Current price$36.8279 per ML
All-time high$38.6398 (Nov 12, 2025)
All-time low$24.9823 (Nov 20, 2024)
52-week high$38.6398
52-week low$33.6338
Median price$34.1832
Average price$33.1628
Largest weekly change+33.8% (Oct 18, 2023)
Weeks tracked169
Tracking sinceJul 12, 2023

Price History

1W

0.0%

1M

+5.0%

3M

+7.7%

6M

+7.6%

1Y

-1.3%

3Y

+39.7%

5Y

N/A

All

+9.2%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Estradiol valerate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Continue researching this drug

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Frequently asked questions

What is the NADAC price of ESTRADIOL VALERATE 200 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL VALERATE 200 MG/5 ML, manufactured by Xiromed LLC, is $36.8279 per ML (NDC 70700027522), effective Sep 30, 2026.

How has the price of ESTRADIOL VALERATE 200 MG/5 ML changed over time?

Over the history we have for it, the NADAC for ESTRADIOL VALERATE 200 MG/5 ML has risen 9.2%. It has been tracked across 169 weekly CMS publications since Jul 12, 2023.

What are the highest and lowest recorded NADAC prices for ESTRADIOL VALERATE 200 MG/5 ML?

Since Jul 12, 2023, the NADAC for ESTRADIOL VALERATE 200 MG/5 ML has ranged from a low of $24.9823 (Nov 20, 2024) to a high of $38.6398 (Nov 12, 2025), with a median of $34.1832 per ML.

Are there cheaper alternatives to ESTRADIOL VALERATE 200 MG/5 ML?

No other NADAC-published product currently shares the active ingredient and strength of ESTRADIOL VALERATE 200 MG/5 ML in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures ESTRADIOL VALERATE 200 MG/5 ML?

ESTRADIOL VALERATE 200 MG/5 ML (NDC 70700027522) is labeled by Xiromed LLC, and CMS classifies it as a generic product.