Product Information
CYANOCOBALAMIN 1,000 MCG/ML VL is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $1.4915 per ML under NDC 70710166307. Its NADAC has been published 193 times since Oct 26, 2022.
FDA first approved this application on Apr 15, 2022. Its Orange Book therapeutic-equivalence code is AP.
Strength
1000 ug/mL
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
70710166307
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; SUBCUTANEOUS
Effective Date
6/17/2026
Active Ingredients
CYANOCOBALAMINApproval Type
Generic (ANDA)
FDA Application
ANDA214655FDA Approved
4/15/2022
TE Code
AP
On Market Since
5/5/2022
Pharmacological Classes
Price Statistics
The NADAC for CYANOCOBALAMIN 1,000 MCG/ML VL has been published 193 times since Oct 26, 2022, and over the history we have for it it has declined 51.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.4915 per ML |
|---|---|
| All-time high | $3.0832 (Jan 11, 2023) |
| All-time low | $1.4915 (Jun 17, 2026) |
| 52-week high | $1.6529 |
| 52-week low | $1.4915 |
| Median price | $1.8691 |
| Average price | $2.0715 |
| Largest weekly change | +39.2% (Aug 21, 2024) |
| Weeks tracked | 193 |
| Tracking since | Oct 26, 2022 |
1W
N/A
1M
N/A
3M
N/A
6M
-0.7%
1Y
-9.8%
3Y
-45.0%
5Y
N/A
All
-51.2%
Last surveyed Jul 1, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 78% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Zydus Pharmaceuticals (USA) Inc. manufacturer profile
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Drug market
cyanocobalamin market comparison
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Therapeutic class
Vitamin B12 class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CYANOCOBALAMIN 1,000 MCG/ML VL?
The current National Average Drug Acquisition Cost (NADAC) for CYANOCOBALAMIN 1,000 MCG/ML VL, manufactured by Zydus Pharmaceuticals (USA) Inc., is $1.4915 per ML (NDC 70710166307), effective Jul 1, 2026.
How has the price of CYANOCOBALAMIN 1,000 MCG/ML VL changed over time?
Over the history we have for it, the NADAC for CYANOCOBALAMIN 1,000 MCG/ML VL has declined 51.2%. It has been tracked across 193 weekly CMS publications since Oct 26, 2022.
What are the highest and lowest recorded NADAC prices for CYANOCOBALAMIN 1,000 MCG/ML VL?
Since Oct 26, 2022, the NADAC for CYANOCOBALAMIN 1,000 MCG/ML VL has ranged from a low of $1.4915 (Jun 17, 2026) to a high of $3.0832 (Jan 11, 2023), with a median of $1.8691 per ML.
Are there cheaper alternatives to CYANOCOBALAMIN 1,000 MCG/ML VL?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CYANOCOBALAMIN 30,000 MCG/30 ML, is $0.3281 per ML — about 78% below CYANOCOBALAMIN 1,000 MCG/ML VL.
Who manufactures CYANOCOBALAMIN 1,000 MCG/ML VL?
CYANOCOBALAMIN 1,000 MCG/ML VL (NDC 70710166307) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.