Product Information

PHENYLEPHRINE 2.5% EYE DROP is a generic product labeled by Lifestar Pharma LLC, priced at $9.2005 per ML under NDC 70756062925. Its NADAC has been published 110 times since Jul 17, 2024.

FDA first approved this application on Sep 29, 2022. Its Orange Book therapeutic-equivalence code is AT.

PHENYLEPHRINE 2.5% EYE DROP

Phenylephrine Hydrochloride
$9.2005per ML

Strength

25 mg/mL

NDC

70756062925

Classification

Generic

Dosage Form

SOLUTION/ DROPS

Route

OPHTHALMIC

Effective Date

8/19/2026

Active Ingredients

PHENYLEPHRINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA216859

FDA Approved

9/29/2022

TE Code

AT

On Market Since

10/7/2022

Pharmacological Classes

Adrenergic alpha1-Agonists
alpha-1 Adrenergic Agonist

Price Statistics

The NADAC for PHENYLEPHRINE 2.5% EYE DROP has been published 110 times since Jul 17, 2024, and over the history we have for it it has declined 29.9%. The table below summarizes its recorded NADAC range and movement.

Current price$9.2005 per ML
All-time high$13.7575 (Nov 13, 2024)
All-time low$8.5534 (Feb 18, 2026)
52-week high$12.7786
52-week low$8.5534
Median price$12.7786
Average price$11.5785
Largest weekly change-12.0% (Nov 19, 2025)
Weeks tracked110
Tracking sinceJul 17, 2024

Price History

1W

-0.8%

1M

-0.8%

3M

+1.3%

6M

+7.6%

1Y

-28.0%

3Y

N/A

5Y

N/A

All

-29.9%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PHENYLEPHRINE 2.5% EYE DROP?

The current National Average Drug Acquisition Cost (NADAC) for PHENYLEPHRINE 2.5% EYE DROP, manufactured by Lifestar Pharma LLC, is $9.2005 per ML (NDC 70756062925), effective Aug 19, 2026.

How has the price of PHENYLEPHRINE 2.5% EYE DROP changed over time?

Over the history we have for it, the NADAC for PHENYLEPHRINE 2.5% EYE DROP has declined 29.9%. It has been tracked across 110 weekly CMS publications since Jul 17, 2024.

What are the highest and lowest recorded NADAC prices for PHENYLEPHRINE 2.5% EYE DROP?

Since Jul 17, 2024, the NADAC for PHENYLEPHRINE 2.5% EYE DROP has ranged from a low of $8.5534 (Feb 18, 2026) to a high of $13.7575 (Nov 13, 2024), with a median of $12.7786 per ML.

Are there cheaper alternatives to PHENYLEPHRINE 2.5% EYE DROP?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PHENYLEPHRINE 2.5% EYE DROP in a comparable dosage form, but none are currently priced below it.

Who manufactures PHENYLEPHRINE 2.5% EYE DROP?

PHENYLEPHRINE 2.5% EYE DROP (NDC 70756062925) is labeled by Lifestar Pharma LLC, and CMS classifies it as a generic product.