Product Information
CLOBETASOL 0.05% CREAM is a generic product labeled by NorthStar Rx LLC, priced at $0.1668 per GM under NDC 72603032302. Its NADAC has been published 83 times since Mar 5, 2025.
FDA first approved this application on Aug 28, 2020. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
NorthStar Rx LLCNDC
72603032302
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA212982FDA Approved
8/28/2020
TE Code
AB1
On Market Since
11/1/2024
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% CREAM has been published 83 times since Mar 5, 2025, and over the history we have for it it has risen 10.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1668 per GM |
|---|---|
| All-time high | $0.1884 (Aug 13, 2025) |
| All-time low | $0.1511 (Mar 5, 2025) |
| 52-week high | $0.1780 |
| 52-week low | $0.1668 |
| Median price | $0.1739 |
| Average price | $0.1737 |
| Largest weekly change | +8.2% (Mar 19, 2025) |
| Weeks tracked | 83 |
| Tracking since | Mar 5, 2025 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 27% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
NorthStar Rx LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Clobetasol Propionate Cream USP, 0.05% market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by NorthStar Rx LLC, is $0.1668 per GM (NDC 72603032302), effective Sep 30, 2026.
How has the price of CLOBETASOL 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has risen 10.4%. It has been tracked across 83 weekly CMS publications since Mar 5, 2025.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?
Since Mar 5, 2025, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.1511 (Mar 5, 2025) to a high of $0.1884 (Aug 13, 2025), with a median of $0.1739 per GM.
Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% CREAM, is $0.1216 per GM — about 27% below CLOBETASOL 0.05% CREAM.
Who manufactures CLOBETASOL 0.05% CREAM?
CLOBETASOL 0.05% CREAM (NDC 72603032302) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.